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Development of small molecule screens for autism using patient-derived iPS cells

  • Post author:
  • Post published:October 14, 2025
  • Post category:

Autism Spectrum Disorders (ASDs) are a heritable group of neuro-developmental disorders characterized by language impairments, difficulties in social integrations, and the presence of stereotyped and repetitive behaviors. There are no…

Continue ReadingDevelopment of small molecule screens for autism using patient-derived iPS cells

Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo

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  • Post published:October 14, 2025
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We aim to develop, test and validate a new, sensitive and affordable scanner for tracking the location of injected cells in humans and animals. This new scanning method, called Magnetic…

Continue ReadingMagnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo

Development of Synthetic Microenvironments for Stem Cell Growth and Differentiation

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  • Post published:October 14, 2025
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Currently, many chronic diseases and injuries do not have effective cures; millions of people suffer from disabilities while carrying on daily lives without appropriate medical assistance. Advances in human pluripotent…

Continue ReadingDevelopment of Synthetic Microenvironments for Stem Cell Growth and Differentiation

Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke

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  • Post published:October 14, 2025
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Stroke is the leading cause of adult disability. Most patients survive their initial stroke, but do not recover fully. Because of incomplete recovery, up to 1/3 of stroke patients are…

Continue ReadingDevelopment of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke

Site-specific integration of Lmx1a, FoxA2, & Otx2 to optimize dopaminergic differentiation

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  • Post published:October 14, 2025
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The objective of this study is to develop a new, optimized technology to obtain a homogenous population of midbrain dopaminergic (mDA) neurons in a culture dish through neuronal differentiation. Dopaminergic…

Continue ReadingSite-specific integration of Lmx1a, FoxA2, & Otx2 to optimize dopaminergic differentiation

Development and Application of Versatile, Automated, Microfluidic Cell Culture System

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  • Post published:October 14, 2025
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Supported in part by a previous CIRM Tools and Technologies Grant [REDACTED], we have optimized and scaled up highly advanced (microfluidic) cell culture chips into manufacturable form, produced prototype instruments…

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Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders

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  • Post published:October 14, 2025
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Our research group at [REDACTED] has had a long-standing interest in understanding the cause of several disorders that result in severe, and often times fatal forms of diarrhea in children.…

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Regeneration of Functional Human Corneal Epithelial Progenitor Cells

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  • Post published:October 14, 2025
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Over 3.2 million people worldwide are bilateral blind from corneal diseases. Limbal stem cell deficiency (LSCD) has been recognized as a major cause, either primary or secondary, of significant visual…

Continue ReadingRegeneration of Functional Human Corneal Epithelial Progenitor Cells

Inhibitory Nerve Cell Precursors: Dosing, Safety and Efficacy

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  • Post published:October 14, 2025
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Many neurological disorders are characterized by an imbalance between excitation and inhibition. Our ultimate goal: to develop a cell-based therapy to modulate aberrant brain activity in the treatment of these…

Continue ReadingInhibitory Nerve Cell Precursors: Dosing, Safety and Efficacy

Liver Cell Transplantation

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  • Post published:October 14, 2025
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Because there is still considerable morbidity and mortality associated with the process of whole liver transplantation, and because more than a thousand people die each year while on the liver…

Continue ReadingLiver Cell Transplantation
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