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microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells

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  • Post published:December 13, 2025
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Regenerative therapies could be particularly beneficial for heart disease, which is the leading killer of adults in the U.S, and is responsible for the 5 million Americans with insufficient cardiac…

Continue ReadingmicroRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells

Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons

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  • Post published:December 13, 2025
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Human embryonic stem cells (hESCs) are pluripotent entities, capable of generating a whole-body spectrum of distinct cell types. We have developmental procedures for inducing hESCs to develop into pure populations…

Continue ReadingMolecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons

Human oocyte development for genetic, pharmacological and reprogramming applications

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  • Post published:December 13, 2025
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Continue ReadingHuman oocyte development for genetic, pharmacological and reprogramming applications

Constructing a fate map of the human embryo

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  • Post published:December 13, 2025
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The United States government does not fund research involving human embryos or cells that were grown from them after August 9, 2001. In addition, other restrictions have been imposed that…

Continue ReadingConstructing a fate map of the human embryo

The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning

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  • Post published:December 13, 2025
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n therapeutic cloning, a patient’s cell is combined (fused) to an enucleated donated egg (oocyte) from an unrelated woman or from another animal. It is hoped that cellular factors in…

Continue ReadingThe Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning

Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

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  • Post published:December 13, 2025
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Alzheimer’s Disease (AD) is a progressive incurable disease that robs people of their memory and ability to think and reason. It is emotionally, and sometimes financially devastating to families that…

Continue ReadingUsing Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cells

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  • Post published:December 13, 2025
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Regenerative medicine holds the promise that tissues can be engineered in vitro and then transplanted into patients to treat debilitating diseases. Human Embryonic Stem Cells differentiate into a wide array…

Continue ReadingFunctional Genomic Analysis of Chemically Defined Human Embryonic Stem Cells

Derivation and characterization of human ES cells from FSHD embryos

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  • Post published:December 13, 2025
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Facioscapulohumeral muscular dystrophy (FSHD) is the third most common hereditary muscular dystrophy. It is autosomal dominant, meaning that if one of the parents has the disease, their children have a…

Continue ReadingDerivation and characterization of human ES cells from FSHD embryos

Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells

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  • Post published:December 13, 2025
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Hair cells (HCs) convert sound and balance signals into electrical impulses in the inner ear, including the cochlea and the vestibular endorgans, with remarkable precision and sensitivity. Our long-term goal…

Continue ReadingHair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells

Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia

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  • Post published:December 13, 2025
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Embryonic stem cells are pluripotent which means they can in principle be instructed to become every cell type in the body. Moreover, they can produce an infinite number of daughter…

Continue ReadingInduction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia
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