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  • About
    • Our Mission
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Understanding the role of LRRK2 in iPSC cell models of Parkinson’s Disease

  • Post author:
  • Post published:May 10, 2025
  • Post category:

The goal of this research is to utilize novel research tools to investigate the molecular mechanisms that cause Parkinson’s disease (PD). The proposed work builds on previous funding from CIRM…

Continue ReadingUnderstanding the role of LRRK2 in iPSC cell models of Parkinson’s Disease

Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

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  • Post published:May 10, 2025
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Stem cell research offers new tools to help treat and cure diseases that affect diverse cells types in the body such as neurological diseases, heart disease and diabetes by producing…

Continue ReadingIdentifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

Ubiquitin-dependent control of hESC self-renewal and expansion

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  • Post published:May 10, 2025
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Human embryonic stem cells (hESCs) or induced pluripotent stem cells (iPSCs) provide an invaluable resource for regenerative medicine and disease modeling. To be able to use these cells in the…

Continue ReadingUbiquitin-dependent control of hESC self-renewal and expansion

Forming the Hematopoietic Niche from Human Pluripotent Stem Cells

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  • Post published:May 10, 2025
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The clinical potential of pluripotent stem cells for use in regenerative medicine will be realized only when the process by which tissues are generated from these cells is significantly more…

Continue ReadingForming the Hematopoietic Niche from Human Pluripotent Stem Cells

Biological relevance of microRNAs in hESC differentiation to endocrine pancreas

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  • Post published:May 10, 2025
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There remains an urgent and critical need for a cell-based cure of diabetes, one of the most costly diseases in California. Islet transplantation with persistent immune suppression has shown promise…

Continue ReadingBiological relevance of microRNAs in hESC differentiation to endocrine pancreas

Induced Pluripotent Stem Cells for Tissue Regeneration

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  • Post published:May 10, 2025
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Induced pluripotent stem cells (iPSCs) have tremendous potential for patient-specific cell therapies, which bypasses immune rejection issues and ethical concerns for embryonic stem cells (ESCs). However, to fully harness the…

Continue ReadingInduced Pluripotent Stem Cells for Tissue Regeneration

Tri-resolution Visualization System for Stem Cells and Tissue Regeneration Monitoring

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  • Post published:May 10, 2025
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The 3D imaging techniques of CT and MRI have virtually eliminated the need for exploratory surgery – a procedure which was common in difficult cases just 20-30 years ago. Not…

Continue ReadingTri-resolution Visualization System for Stem Cells and Tissue Regeneration Monitoring

Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders

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  • Post published:May 10, 2025
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Our research group at [REDACTED] has had a long-standing interest in understanding the cause of several disorders that result in severe, and often times fatal forms of diarrhea in children.…

Continue ReadingPluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders

Engineering microscale tissue constructs from human pluripotent stem cells

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  • Post published:May 10, 2025
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Tissues derived from stem cells can serve multiple purposes to enhance biomedical therapies. Human tissues engineered from stem cells hold tremendous potential to serve as better substrates for the discovery…

Continue ReadingEngineering microscale tissue constructs from human pluripotent stem cells

Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

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  • Post published:May 10, 2025
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Bone marrow and peripheral blood transplantation utilizing blood stem cells can provide curative treatment for patients with cancers and non-cancerous diseases of the blood and immune systems. Such treatments can…

Continue ReadingNiche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors
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