Xavier Darzacq
Institution Name:
University of California, Berkeley
Total Awards:
1
Award Value:
$4,175,924
Awards as PI
| Program Type | Institution | Grant Title | Award Value |
|---|---|---|---|
| Research Leadership | University of California, Berkeley | Single Molecule Biophysics and Biology of Cellular Identity | $4,175,924 |
Total: $4,175,924.00 |
Publications
- Elife 2016 A dynamic mode of mitotic bookmarking by transcription factors. (PubMed: 27855781)
- Elife 2017 CTCF and cohesin regulate chromatin loop stability with distinct dynamics. (PubMed: 28467304)
- Nat Commun 2017 Live cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9. (PubMed: 28290446)
- Elife 2018 Robust model-based analysis of single-particle tracking experiments with Spot-On. (PubMed: 29300163)
- Biochem Soc Trans 2018 Protein motion in the nucleus: from anomalous diffusion to weak interactions. (PubMed: 30065106)
- Methods Mol Biol 2018 Single Molecule Imaging in Live Embryos Using Lattice Light-Sheet Microscopy. (PubMed: 29956254)
- Nucleus 2018 Recent evidence that TADs and chromatin loops are dynamic structures. (PubMed: 29077530)
- Mol Biol Cell 2017 Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage. (PubMed: 28794266)
- Genes Dev 2017 A dynamic interplay of enhancer elements regulates Klf4 expression in naive pluripotency. (PubMed: 28982762)
- Nature 2017 Phase separation drives heterochromatin domain formation. (PubMed: 28636597)
- Nat Commun 2016 A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting. (PubMed: 27461529)
- Biomed Opt Express 2016 Multifocus microscopy with precise color multi-phase diffractive optics applied in functional neuronal imaging. (PubMed: 27231594)
- Genes Dev 2017 Dense Bicoid hubs accentuate binding along the morphogen gradient. (PubMed: 28982761)
- Elife 2018 Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos. (PubMed: 30589412)
- Science 2018 Imaging dynamic and selective low-complexity domain interactions that control gene transcription. (PubMed: 29930090)
- Elife 2018 A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes. (PubMed: 29939130)
- Nat Struct Mol Biol 2018 RNA polymerase II clustering through carboxy-terminal domain phase separation. (PubMed: 30127355)
- Elife 2019 Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. (PubMed: 31038454)
- Opt Express 2017 Faster and less phototoxic 3D fluorescence microscopy using a versatile compressed sensing scheme. (PubMed: 28788909)
- Genome Res 2019 CTCF sites display cell cycle-dependent dynamics in factor binding and nucleosome positioning. (PubMed: 30655336)
- Elife 2019 Determining cellular CTCF and cohesin abundances to constrain 3D genome models. (PubMed: 31205001)
- Mol Cell 2019 Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. (PubMed: 31522987)
- Genes Dev 2019 Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. (PubMed: 31594803)
- Nat Chem Biol 2020 Guided nuclear exploration increases CTCF target search efficiency. (PubMed: 31792445)
- Mol Cell 2020 Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding. (PubMed: 32213323)