Matthew Porteus

Institution Name:

Stanford University

Total Awards:

5

Award Value:

$25,177,328

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Awards as PI

Program Type	Institution	Grant Title	Award Value
Preclinical Development Awards	Stanford University	Pre-clinical development of gene correction therapy of hematopoietic stem cells for SCID-X1	$874,877
Quest - Discovery Stage Research Projects	Stanford University	Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells	$1,968,456
Late Stage Preclinical Projects	Stanford University	Genome Editing of Autologous Hematopoietic Stem Cells to Treat Sickle Cell Disease	$4,849,363
Clinical Trial Stage Projects	Stanford University	Phase 1/1b study of T-allo10 infusion after HLA-partially matched abdepleted-HSCT in children and young adults with hematologic malignancies.	$10,563,822
Alpha Stem Cell Clinics Network Expansion	Stanford University	The Stanford Alpha Stem Cell Clinic	$6,920,810
			Total: $25,177,328.00

Publications

Nat Med 2018 A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells. (PubMed: 30082871)
Cell Stem Cell 2019 High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. (PubMed: 31839569)