Mark Mercola
Institution Name:
Sanford Burnham Prebys Medical Discovery Institute
Total Awards:
2
Award Value:
$3,893,865
Awards as PI
| Program Type | Institution | Grant Title | Award Value |
|---|---|---|---|
| Comprehensive Grant | Sanford Burnham Prebys Medical Discovery Institute | Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes | $2,832,000 |
| Training Grant I-2 | Sanford Burnham Prebys Medical Discovery Institute | Burnham Institute CIRM Stem Cell Training Grant (Type II) | $1,061,865 |
Total: $3,893,865.00 |
Awards as Co-PI
| Early Translational IV | Improving Existing Drugs for Long QT Syndrome type 3 (LQT3) by hiPSC Disease-in-Dish Model |
Publications
- Cell Stem Cell 2012 Small Molecule-Mediated TGF-beta Type II Receptor Degradation Promotes Cardiomyogenesis in Embryonic Stem Cells. (PubMed: 22862949)
- Genes Dev 2012 Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. (PubMed: 23152446)
- Curr Protoc Stem Cell Biol 2012 Serum-free generation of multipotent mesoderm (kdr(+)) progenitor cells in mouse embryonic stem cells for functional genomics screening. (PubMed: 23154934)
- PLoS One 2009 Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. (PubMed: 19352491)
- PLoS One 2008 Contrasting expression of keratins in mouse and human embryonic stem cells. (PubMed: 18941637)
- Dev Biol 2007 Multiple functions of Cerberus cooperate to induce heart downstream of Nodal. (PubMed: 17123501)
- Pediatr Cardiol 2009 Natural and synthetic regulators of embryonic stem cell cardiogenesis. (PubMed: 19319460)
- J Med Chem 2012 Synthesis and SAR of b-Annulated 1,4-Dihydropyridines Define Cardiomyogenic Compounds as Novel Inhibitors of TGFbeta Signaling. (PubMed: 23130626)
- J Cardiovasc Transl Res 2011 A chemical biology approach to myocardial regeneration. (PubMed: 21424858)
- Sci Rep 2013 Quantitative Transcriptomics using Designed Primer-based Amplification. (PubMed: 23624976)
- Stem Cells Dev 2010 Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation. (PubMed: 20001453)
- Dev Biol 2008 A novel activity of the Dickkopf-1 amino terminal domain promotes axial and heart development independently of canonical Wnt inhibition. (PubMed: 18840423)
- Assay Drug Dev Technol 2008 A comparative analysis of standard microtiter plate reading versus imaging in cellular assays. (PubMed: 18795873)
- PLoS Comput Biol 2009 Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors. (PubMed: 19893621)
- Ann N Y Acad Sci 2010 Cardiac myocyte force development during differentiation and maturation. (PubMed: 20201894)
- Circulation 2009 Electrophysiological challenges of cell-based myocardial repair. (PubMed: 20008740)
- Proc Natl Acad Sci U S A 2010 Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. (PubMed: 20498046)
- Mol Cell 2011 Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. (PubMed: 22099302)
- Nature 2014 Inhibition of miR-25 improves cardiac contractility in the failing heart. (PubMed: 24670661)
