Fred Gage
Institution Name:
Salk Institute for Biological Studies
Total Awards:
3
Award Value:
$6,959,852
Awards as PI
Program Type | Institution | Grant Title | Award Value |
---|---|---|---|
Early Translational II | Salk Institute for Biological Studies | Crosstalk: Inflammation in Parkinson’s disease (PD) in a humanized in vitro model | $2,472,839 |
New Cell Lines | Salk Institute for Biological Studies | Development of Induced Pluripotent Stem Cells for Modeling Human Disease | $1,737,720 |
Comprehensive Grant | Salk Institute for Biological Studies | Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons | $2,749,293 |
Total: $6,959,852.00 |
Publications
- Cell 2010 A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells. (PubMed: 21074045)
- Nature 2009 L1 retrotransposition in human neural progenitor cells. (PubMed: 19657334)
- PLoS One 2010 High-efficient generation of induced pluripotent stem cells from human astrocytes. (PubMed: 21170306)
- Nat Struct Mol Biol 2009 An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. (PubMed: 19136955)
- Cell 2009 A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. (PubMed: 19345186)
- Hum Mol Genet 2008 Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells. (PubMed: 18632700)
- Hum Mol Genet 2010 Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. (PubMed: 20418487)
- Cell 2010 Mechanisms underlying inflammation in neurodegeneration. (PubMed: 20303880)
- Cell Stem Cell 2008 Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. (PubMed: 19041781)
- PLoS Comput Biol 2007 Alternative splicing events identified in human embryonic stem cells and neural progenitors. (PubMed: 17967047)
- Eur J Neurosci 2011 Neurodegenerative disease and adult neurogenesis. (PubMed: 21395858)
- Proc Natl Acad Sci U S A 2011 Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. (PubMed: 22159035)
- Cell Stem Cell 2012 Modeling brain disease in a dish: really? (PubMed: 22704498)
- Proc Natl Acad Sci U S A 2012 Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. (PubMed: 22814375)
- Curr Protoc Stem Cell Biol 2012 Dopaminergic differentiation of human pluripotent cells. (PubMed: 22872424)
- PLoS One 2009 Transcriptional signature and memory retention of human-induced pluripotent stem cells. (PubMed: 19763270)
- Stem Cell Reports 2014 Modeling hippocampal neurogenesis using human pluripotent stem cells. (PubMed: 24672753)
- Neuron 2014 Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. (PubMed: 24726381)
- Hum Mol Genet 2014 Human induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. (PubMed: 24821704)