Donald Kohn

Institution Name:

University of California, Los Angeles

Total Awards:

5

Award Value:

$30,744,407

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Awards as PI

Program Type	Institution	Grant Title	Award Value
Disease Team Research I	University of California, Los Angeles	Stem Cell Gene Therapy for Sickle Cell Disease	$8,833,695
Early Translational IV	University of California, Los Angeles	Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells	$1,652,076
Disease Team Therapy Development III	University of California, Los Angeles	Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease	$13,145,465
Clinical Trial Stage Projects	University of California, Los Angeles	A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease	$7,083,364
Conference II	University of California, Los Angeles	Primary Immune Deficiency Treatment Consortium (PIDTC) Annual Scientific Workshop	$29,807
			Total: $30,744,407.00

Publications

J Clin Invest 2013 beta-globin gene transfer to human bone marrow for sickle cell disease. (PubMed: 23863630)
Cytotherapy 2017 Preclinical studies for a phase 1 clinical trial of autologous hematopoietic stem cell gene therapy for sickle cell disease. (PubMed: 28733131)
Stem Cells 2018 Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair. (PubMed: 30372555)

Videos

Stem Cell Gene Therapy for Sickle Cell Anemia - Donald Kohn	Stem Cell Cure for "Bubble Baby" Disease (SCID), Pioneered by UCLA's Don Kohn
Defeating Sickle Cell Disease with Stem Cells + Gene Therapy