Diana Farmer
Institution Name:
University of California, Davis
Total Awards:
3
Award Value:
$16,793,827
Awards as PI
| Program Type | Institution | Grant Title | Award Value |
|---|---|---|---|
| Preclinical Development Awards | University of California, Davis | Placental Stem Cells for the In Utero Treatment of Spina Bifida | $2,182,146 |
| Late Stage Preclinical Projects | University of California, Davis | Placental Mesenchymal Stem Cell Augmentation of Fetal Myelomeningocele Repair | $5,615,207 |
| Clinical Trial Stage Projects | University of California, Davis | The CuRe Trial: Cellular Therapy for In Utero Myelomeningocele Repair | $8,996,474 |
Total: $16,793,827.00 |
Publications
- Placenta 2017 Effect of 2-octylcyanoacrylate on placenta derived mesenchymal stromal cells on extracellular matrix. (PubMed: 28465002)
- Cytotherapy 2017 Manufacture and preparation of human placenta-derived mesenchymal stromal cells for local tissue delivery. (PubMed: 28438482)
- J Pediatr Surg 2017 Placental mesenchymal stromal cells seeded on clinical grade extracellular matrix improve ambulation in ovine myelomeningocele. (PubMed: 29122293)
- J Pediatr Surg 2017 Fetal surgical repair with placenta-derived mesenchymal stromal cell engineered patch in a rodent model of myelomeningocele. (PubMed: 29096888)
- Placenta 2017 Potential clinical applications of placental stem cells for use in fetal therapy of birth defects. (PubMed: 28651900)
- J Pediatr Surg 2018 High density placental mesenchymal stromal cells provide neuronal preservation and improve motor function following in utero treatment of ovine myelomeningocele. (PubMed: 30529115)
- FASEB J 2019 Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes. (PubMed: 30753093)
- Fetal Diagn Ther 2019 Spinal Angulation: A Limitation of the Fetal Lamb Model of Myelomeningocele. (PubMed: 30970373)
- J Pediatr Surg 2019 In Utero Treatment of Myelomeningocele with Placental Mesenchymal Stromal Cells - Selection of an Optimal Cell Line in Preparation for Clinical Trials. (PubMed: 31672407)
- World J Stem Cells 2020 Clonal isolation of endothelial colony-forming cells from early gestation chorionic villi of human placenta for fetal tissue regeneration. (PubMed: 32184937)
- Fetal Diagn Ther 2020 A Decade of Experience with the Ovine Model of Myelomeningocele: Risk Factors for Fetal Loss. (PubMed: 32097922)
- Fetal Diagn Ther 2020 Surviving Lambs with Myelomeningocele Repaired in utero with Placental Mesenchymal Stromal Cells for 6 Months: A Pilot Study. (PubMed: 33166951)
- J Pediatr Surg 2021 Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model. (PubMed: 34657738)
- Lab Anim 2021 Minimizing the risk of occupational Q fever exposure: A protocol for ensuring Coxiella burnetii-negative pregnant ewes are used for medical research. (PubMed: 33108940)
- J Surg Res 2021 Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair. (PubMed: 34273796)
- J Pediatr Surg 2021 Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair. (PubMed: 34217509)
- Fetal Diagn Ther 2021 A Novel Model of Fetal Spinal Cord Exposure Allowing for Long-Term Postnatal Survival. (PubMed: 34111873)
- Cells 2021 The Unique Properties of Placental Mesenchymal Stromal Cells: A Novel Source of Therapy for Congenital and Acquired Spinal Cord Injury. (PubMed: 34831060)
- J Pediatr Surg 2022 Early investigations into improving bowel and bladder function in fetal ovine myelomeningocele repair. (PubMed: 35093254)
- J Surg Res 2022 Impact of Gestational Age on Neuroprotective Function of Placenta-Derived Mesenchymal Stromal Cells. (PubMed: 35093836)
- Bioact Mater 2023 A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. (PubMed: 35663336)
- Theranostics 2022 Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. (PubMed: 35966577)
- J Dev Biol 2022 Spina Bifida: A Review of the Genetics, Pathophysiology and Emerging Cellular Therapies. (PubMed: 35735913)