Grant Award Details

Development of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice.
Grant Number: 
TRX-01431
Project Objective: 
  • Goal of the project is to develop a humanized mouse model for transplantation of HIV infected mice and to demonstrate disease modifying activity of gene modified CD34 encoding anti-HIV shRNA in the progeny immune cells after transplantation in this animal model.
Investigator: 
Name: 
Type: 
PI
Disease Focus: 
HIV/AIDS
Infectious Disease
Human Stem Cell Use: 
Adult Stem Cell
Award Value: 
$1,505,000
Status: 
Closed

Progress Reports

Reporting Period: 
Year 1
Reporting Period: 
Year 2 + NCE

Grant Application Details

Application Title: 
  • HPSC based therapy for HIV disease using RNAi to CCR5.
Public Abstract: 
Statement of Benefit to California: