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Institution:
Type:
PI
Research Objective
HSC-engineered allogeneic mesothelin-targeting CAR-iNKT (AlloMCAR-iNKT) cells
Impact
treatment of ovarian cancer
Major Proposed Activities
Ovarian cancer (OC) is the leading cause of death among women with gynecological malignancies. In the USA, California is the state with the highest incidences and deaths of ovarian cancer. In 2021, it is estimated that 2,550 women will be diagnosed with OC and 1,640 women will die from this disease at California. Therefore, novel therapies are urgently needed. The proposed project can potentially lead to a novel off-the-shelf cell therapy for ovarian cancer and save lives