Central Nervous System (CNS) Consortium Workshop
As articulated in our 2022-2027 strategic plan, CIRM is committed to continued funding of high-risk/high-reward research projects through our existing pillar programs, and to promote their success by building infrastructure that fosters shared usage of specialized technologies, and organizes and democratizes data through knowledge networks.
In February 2022, CIRM hosted a Central Nervous System (CNS) Consortium Workshop, bringing together ~40 key opinion leaders and stakeholders to explore the feasibility and possible approaches for a first deployment of these two resources through:
A network of Shared Resources Laboratories that innovate, validate and share stem cell-based models to support California regenerative medicine researchers,
A Data Infrastructure where CIRM-funded data can be shared and external datasets leveraged to maximize real-world impact.
While the discussions at the workshop centered on applications to the CNS, the shared resources will be implemented broadly across cell types and organs. The Data Infrastructure is intended to be a global resource for data sharing and fostering a culture of open science for all CIRM grantees — and the world.
You can read more about the workshop and our goals on our blog, The Stem Cellar.
Access materials from the workshop using the links below:
- CNS Consortium Workshop Agenda
- Day 1 Summary: Shared Resources Laboratories for Stem Cell-Based Modeling
- Day 2 Summary: Data Infrastructure
YouTube videos of workshop
- February 24, 2022: CIRM CNS Consortium Workshop Day 1: What are the opportunities to share resources and promote collaborative research?
- February 25, 2022: CIRM CNS Consortium Workshop Day 2: What is the best approach to promoting data sharing among California researchers?
- Workshop Introduction: Day 1
- Session I (Introduction: Overview of CIRM-funded Research Resources)
- CIRM Shared Research Laboratory Grants and Stem Cell Techniques Course
- Leveraging Large iPSC Cohorts and Population Scale Stem Cell Models to Study the Effect of Genetic Variation on Cellular Phenotypes
- CIRM hiPSC Repository: NAFLD Lines for Disease Modeling
- Machine Learning for Unraveling the Complex Biology of CNS Disease
- CIRM Genomics Stem Cell Hub: Experimental-Computational Collaboration to Characterize Cortical Organoids
- Session II (Introduction: Shared Resources Labs – Moderated Discussion)
- Workshop Introduction: Day 2 (Session III)
- Data Biosphere: An Introduction
- Collaborating in the Cloud – AMP PD / Terra
- Cloud-based Collaborative Research in Neurodegenerative Diseases
- Migrate Your Genomic Research to the Cloud
- CARD long-read seq project using the cloud as only option
- DUOS & GA4GH Standards
- Session IV (Introduction: Data Infrastructure – Moderated Discussion)
- Session IV (Exercise: Data Infrastructure – Moderated Discussion)