Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons
One of the main objectives of stem cell biology is to create physiologically relevant cell types that can be used to either facilitate the study of or directly treat human…
A Phase I/IIa Dose Escalation Safety Study of AST-OPC1 in Patients with Cervical Sensorimotor Complete Spinal Cord Injury
Up to 12,000 Americans suffer a spinal cord injury (SCI) each year. This condition leads to a high level of permanent disability and decreased life expectancy. Currently, there are no…
Evaluation of Safety and Preliminary Efficacy of Escalating Doses of GRNOPC1 in Subacute Spinal Cord Injury
Geron carried out a Phase 1 clinical trial to assess the safety and preliminary activity of escalating doses of human embryonic stem cell (hESC) derived oligodendrocyte progenitor cells for treatment…
Spinal Cord Injury and Stem Cells: Jake Javier, Clinical Trial Participant
On June 9th, 2016, Jake Javier seriously injured his spinal cord in a freak accident after diving into a swimming pool just one day before he was due to graduate…
CURED: Stem Cell Clinical Trial Stories
Clinical trials are risky and rely on brave pioneers who are willing to put their bodies on the line to test something never before tried in people. At its December…
Spinal Cord Injury and a CIRM-Funded Stem Cell-Based Trial
Jane Lebkowski, Asterias Biotherapeutics' VP of R&D, spoke to CIRM's governing Board about the company's CIRM-funded clinical trial for spinal cord injury. Richard Lajara, the fourth participant in a previous…
Spinal Cord Injury and Stem Cell-Based Trials: What’s the Latest?
In this Google Hangout, Jane Lebkowski, PhD, president of research and development at Asterias Biotherapeutics, and Kevin Whittlesey, PhD, a CIRM science officer discuss the latest progress in stem cell-based…
World’s 1st Human Embryonic Stem Cell Trial for Spinal Cord Injury – Katie Sharify
Katie Sharify was one of five people with spinal cord injuries to participate in the world's first clinical trial testing human embryonic stem cells. The Geron sponsored trial was supported…
Roman Reed: What all patient advocates at the World Stem Cell Summit should know
Roman Reed spoke with CIRM at the World Stem Cell Summit about what he thinks patients advocates should know about stem cell research. He came to the meeting in Pasadena…
