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Telomerase mRNA for short telomere related pulmonary fibrosis

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  • Post published:June 5, 2025
  • Post category:

Translational Candidate Nucleoside-modified mRNA encoding telomerase reverse transcriptase (TERT) encapsulated in a lung-targeting lipid nanoparticle delivered intravenously. Area of Impact 1) Idiopathic pulmonary fibrosis (IPF) and 2) Other diseases and…

Continue ReadingTelomerase mRNA for short telomere related pulmonary fibrosis

Autologous Gene Corrected Sinus Basal Cells to Treat Serious Cystic Fibrosis Sinus Disease

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  • Post published:June 5, 2025
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Therapeutic Candidate or Device Gene corrected autologous sinus airway basal stem cells from patients with Cystic Fibrosis. Indication The proposed studies provide an innovative stem cell based approach with gene…

Continue ReadingAutologous Gene Corrected Sinus Basal Cells to Treat Serious Cystic Fibrosis Sinus Disease

Innate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man

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  • Post published:June 5, 2025
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The lung, along with the skin and gut are the three organs in perpetual contact with our environment. The lung has evolved mechanisms for repairing injury due to exogenous noxious…

Continue ReadingInnate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man

Tissue Engineered Recellularized Laryngotracheal Implants

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  • Post published:June 5, 2025
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The goal is to bring a safe and effective therapy to adult patients with critical narrowing of the upper windpipe (trachea) and lower voicebox (larynx). Our intent is to implement…

Continue ReadingTissue Engineered Recellularized Laryngotracheal Implants

Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis

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  • Post published:June 5, 2025
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Idiopathic Pulmonary Fibrosis (IPF) is a progressive and generally fatal disease that causes scarring of the lungs and therefore an inability to breathe. Its true prevalence is unknown, as it…

Continue ReadingUsing human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis

Airways for Children

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  • Post published:June 5, 2025
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The primary goal is to bring a safe and effective therapy to children with severe large airway disease. Our intent is to implement all of the necessary steps for a…

Continue ReadingAirways for Children

Matthew Donne, UCSF – CIRM Stem Cell #SciencePitch

  • Post author:cirmadmin
  • Post published:March 19, 2013
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Continue ReadingMatthew Donne, UCSF – CIRM Stem Cell #SciencePitch

Youngtae Jeong, Stanford – CIRM Stem Cell #SciencePitch

  • Post author:cirmadmin
  • Post published:March 19, 2013
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Continue ReadingYoungtae Jeong, Stanford – CIRM Stem Cell #SciencePitch

Asaf Presente, UCSD – CIRM Stem Cell #SciencePitch

  • Post author:cirmadmin
  • Post published:March 19, 2013
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Continue ReadingAsaf Presente, UCSD – CIRM Stem Cell #SciencePitch
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