Cancer is the leading cause of death for individuals under 85. Relapse and metastatic disease are the leading causes of cancer related mortality. Anti-apoptotic BCL2 family member overexpression has been…
Bone marrow and peripheral blood transplantation utilizing blood stem cells can provide curative treatment for patients with cancers and non-cancerous diseases of the blood and immune systems. Such treatments can…
Various cells and organs in the human body originate from a small group of primitive cells called stem cells. Human cancer cells were also recently found to arise from a…
During an individual’s lifetime, blood-forming cells in the bone marrow called hematopoietic stem cells (HSCs) supply all the red and white blood cells needed to sustain life. These blood stem…
Adult stem cells play an essential role in the maintenance of tissue homeostasis. Environmental and therapeutic insults leading to DNA damage dramatically impact stem cell functions and can lead to…
On March 25th, 2014, California's Stem Cell Agency (CIRM) hosted a live Google Hangout about recent progress in stem cell based treatment strategies for leukemia. Guest experts included CIRM grantees…
Daniel Goff speaks at the 2011 CIRM Grantee Meeting about identifying potential leukemia drugs that could zero-in on and kill the cancer stems cells that are thought to be responsible…
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