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Molecules to Correct Aberrant RNA Signature in Human Diseased Neurons

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  • Post published:August 1, 2025
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Approximately 5,600 people in the U.S. are diagnosed with ALS each year. The incidence of ALS is two per 100,000 people, and it is estimated that as many as 30,000…

Continue ReadingMolecules to Correct Aberrant RNA Signature in Human Diseased Neurons

Stem Cells Secreting GDNF for the Treatment of ALS

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  • Post published:August 1, 2025
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This project aims to use a powerful combined stem cell and gene therapy approach to treat patients with amyotrophic lateral sclerosis (ALS or Lou Gehrig’s Disease). ALS is a devastating…

Continue ReadingStem Cells Secreting GDNF for the Treatment of ALS

Neural and general splicing factors control self-renewal, neural survival and differentiation

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  • Post published:August 1, 2025
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Human embryonic and patient-specific induced pluripotent stem cells have the remarkable capacity to differentiate into many cell-types, including neurons, thus enabling the modeling of human neurological diseases in vitro, and…

Continue ReadingNeural and general splicing factors control self-renewal, neural survival and differentiation

Molecular Imaging for Stem Cell Science and Clinical Application

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  • Post published:August 1, 2025
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Stem cells offer tremendous potential to treat previously intractable diseases. The clinical translation of these therapies, however, presents unique challenges. One challenge is the absence of robust methods to monitor…

Continue ReadingMolecular Imaging for Stem Cell Science and Clinical Application

Molecular mechanisms of neural stem cell differentiation in the developing brain

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  • Post published:August 1, 2025
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One of the most exciting possibilities in stem cell biology is the potential to replace damaged or diseased neural tissues affected by neurodegenerative disorders. Stem-cell-derived neurons provide a potentially limitless…

Continue ReadingMolecular mechanisms of neural stem cell differentiation in the developing brain

Facebook Live: Stem Cells and ALS

  • Post author:cirmadmin
  • Post published:July 31, 2018
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This Facebook Live event, "Ask the Stem Cell Team about ALS", aired on July 31st, 2018 and featured a conversation between Drs. Clive Svendsen, Robert Baloh from Cedars-Sinai, Dr. Ralph…

Continue ReadingFacebook Live: Stem Cells and ALS

Stem Cells in Your Face: Treating ALS with a Disease in a Dish

  • Post author:cirmadmin
  • Post published:September 18, 2014
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To a stem cell scientist, "Disease in a Dish" describes a powerful way to study human disease in the lab using a Nobel Prize winning technique. But to a non-scientist…

Continue ReadingStem Cells in Your Face: Treating ALS with a Disease in a Dish

Google Hangout: Progress Toward Stem Cell Therapies for ALS

  • Post author:cirmadmin
  • Post published:July 8, 2013
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On July 3rd, CIRM hosted a Google Hangout to discuss progress toward stem cell therapies for Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease. Dr. Clive Svendsen, a…

Continue ReadingGoogle Hangout: Progress Toward Stem Cell Therapies for ALS

Webinar: Injecting Neural Stem Cells into ALS Patients: Results of a Phase 1 Trial | Jonathan Glass

  • Post author:cirmadmin
  • Post published:May 6, 2013
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Title: Lumbar Intraspinal Injection of Neural Stem Cells in Patients with ALS:  Results of a Phase I Trial in 12 Patients Speaker: Jonathan D. Glass, M.D. Professor, Neurology and Pathology,…

Continue ReadingWebinar: Injecting Neural Stem Cells into ALS Patients: Results of a Phase 1 Trial | Jonathan Glass

$18 Million ALS Research Grant for Stem Cell Therapy Applauded by ALS Advocates

  • Post author:cirmadmin
  • Post published:July 26, 2012
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On July 26th 2012, the governing board of California's Stem Cell Agency approved an $18 million Disease Team research grant that aims to bring a stem cell-based ALS treatment to…

Continue Reading$18 Million ALS Research Grant for Stem Cell Therapy Applauded by ALS Advocates
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