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Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair

  • Post author:
  • Post published:May 20, 2025
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The advent of human embryonic stem cells (hESCs) has offered enormous potential for regenerative medicine and for basic understanding of human biology. On the one hand, hESCs can be turned…

Continue ReadingGenetic manipulation of human embryonic stem cells and its application in studying CNS development and repair

Gene regulatory mechanisms that control spinal neuron differentiation from hES cells.

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  • Post published:May 20, 2025
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More than 600 disorders afflict the nervous system. Common disorders such as stroke, epilepsy, Parkinson’s disease and autism are well-known. Many other neurological disorders are rare, known only to the…

Continue ReadingGene regulatory mechanisms that control spinal neuron differentiation from hES cells.

In vitro differentiation of hESCs into corticospinal motor neurons

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  • Post published:May 20, 2025
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Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, fatal neurological disease that leads to the degeneration of motor neurons in the brain and in the spinal cord. There are currently…

Continue ReadingIn vitro differentiation of hESCs into corticospinal motor neurons

Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis

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  • Post published:May 20, 2025
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Amyotrophic lateral sclerosis (ALS), a lethal disease lacking effective treatments, is characterized by the loss of upper and lower motor neurons. 5-10% of ALS is familial, but the majority of…

Continue ReadingStem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis

Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons

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  • Post published:May 20, 2025
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One of the main objectives of stem cell biology is to create physiologically relevant cell types that can be used to either facilitate the study of or directly treat human…

Continue ReadingMolecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons

Facebook Live: Stem Cells and ALS

  • Post author:cirmadmin
  • Post published:July 31, 2018
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This Facebook Live event, "Ask the Stem Cell Team about ALS", aired on July 31st, 2018 and featured a conversation between Drs. Clive Svendsen, Robert Baloh from Cedars-Sinai, Dr. Ralph…

Continue ReadingFacebook Live: Stem Cells and ALS

Stem Cells in Your Face: Treating ALS with a Disease in a Dish

  • Post author:cirmadmin
  • Post published:September 18, 2014
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To a stem cell scientist, "Disease in a Dish" describes a powerful way to study human disease in the lab using a Nobel Prize winning technique. But to a non-scientist…

Continue ReadingStem Cells in Your Face: Treating ALS with a Disease in a Dish

Google Hangout: Progress Toward Stem Cell Therapies for ALS

  • Post author:cirmadmin
  • Post published:July 8, 2013
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On July 3rd, CIRM hosted a Google Hangout to discuss progress toward stem cell therapies for Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease. Dr. Clive Svendsen, a…

Continue ReadingGoogle Hangout: Progress Toward Stem Cell Therapies for ALS

Webinar: Injecting Neural Stem Cells into ALS Patients: Results of a Phase 1 Trial | Jonathan Glass

  • Post author:cirmadmin
  • Post published:May 6, 2013
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Title: Lumbar Intraspinal Injection of Neural Stem Cells in Patients with ALS:  Results of a Phase I Trial in 12 Patients Speaker: Jonathan D. Glass, M.D. Professor, Neurology and Pathology,…

Continue ReadingWebinar: Injecting Neural Stem Cells into ALS Patients: Results of a Phase 1 Trial | Jonathan Glass

$18 Million ALS Research Grant for Stem Cell Therapy Applauded by ALS Advocates

  • Post author:cirmadmin
  • Post published:July 26, 2012
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On July 26th 2012, the governing board of California's Stem Cell Agency approved an $18 million Disease Team research grant that aims to bring a stem cell-based ALS treatment to…

Continue Reading$18 Million ALS Research Grant for Stem Cell Therapy Applauded by ALS Advocates
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