Shared Resource Laboratory for Stem Cell-Based Modeling: Resources for Exploring the Biological Underpinnings of Aging and Age-Associated Pathologies
We seek to engage more Californians in stem cell research by providing access to cell models (including those for modeling the aging brain) derived from a uniquely characterize human cohort,…
Utilizing Age-Specific Adipocyte Progenitor Cells for Cell Therapy in Older Patients
Research Objective A new type of APC serves older patients as 1) better MSC in immunomodulation (reducing inflammation) for autologous transplantation; 2) better source of somatic cells for generating heathier…
Examining the efficacy of GDF11 antibody as a rejuvenator of aged human muscle stem cell capacity and muscle repair .
Research Objective To examine the efficacy of blocking blood borne GDF11 activity to rejuvenate aged human muscle stem cell regenerative capacity. Impact This project will provide a proof-of-principle that GDF11…