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WNT signaling and the control of cell fate decisions in human pluripotent stem cells.

  • Post author:
  • Post published:November 21, 2025
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With their ability to develop into virtually all mature cell types, human pluripotent stem cells (hPSC) represent a unique and powerful research tool to study the fundamental mechanisms regulating human…

Continue ReadingWNT signaling and the control of cell fate decisions in human pluripotent stem cells.

The stem cell microenvironment in the maintenance of pluripotency and reprogramming

  • Post author:
  • Post published:November 21, 2025
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Pluripotent stem cell research is just on the verge of beginning to fulfill its promise to revolutionize medicine. Whether they are derived from embryos, or from adult cells that have…

Continue ReadingThe stem cell microenvironment in the maintenance of pluripotency and reprogramming

Defining the molecular mechanisms of somatic cell reprogramming

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  • Post published:November 21, 2025
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The development of methods to “reprogram” adult cells such as skin cells by simultaneously expressing four specific factors — Oct3/4, Sox2, c-Myc and Klf4 — in order to create cells…

Continue ReadingDefining the molecular mechanisms of somatic cell reprogramming
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