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Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

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  • Post published:June 9, 2025
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Alzheimer’s Disease (AD) is a progressive incurable disease that robs people of their memory and ability to think and reason. It is emotionally, and sometimes financially devastating to families that…

Continue ReadingUsing Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

Reprogramming Differentiated Human Cells to a Pluripotent State

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  • Post published:June 9, 2025
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If the therapeutic potential of human embryonic stem (ES) cells is to be realized, the ability to produce pluripotent stem cells with defined genetic backgrounds is essential. Pluripotent cells, through…

Continue ReadingReprogramming Differentiated Human Cells to a Pluripotent State

Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency

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  • Post published:June 9, 2025
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Pluripotent stem cells have a remarkable potential to develop into virtually any cell type of the body, making them a powerful tool for the study or direct treatment of human…

Continue ReadingCellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency

The function of YAP in human embryonic stem cells

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  • Post published:June 9, 2025
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Embryonic stem cells have the potential to generate all tissue types that could be used for regenerative medicine, such as replacement of damaged neurons, replenish of insulin secreting beta cells,…

Continue ReadingThe function of YAP in human embryonic stem cells

Endothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes

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  • Post published:June 9, 2025
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Cardiovascular diseases remain the major cause of death in the western world. Stem and progenitor cell-derived cardiomyocytes (SPC-CMs) hold great promise for myocardial repairs. However, most SPC-CMs displayed heterogeneous and…

Continue ReadingEndothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes

Self-renewal and senescence in iPS cells derived from patients with a stem cell disease

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  • Post published:June 9, 2025
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The discovery of induced pluripotent stem (iPS) cell technology promises to revolutionize our understanding of human disease and to allow the development of new cellular therapies for regenerative medicine applications.…

Continue ReadingSelf-renewal and senescence in iPS cells derived from patients with a stem cell disease

iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa

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  • Post published:June 9, 2025
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Genetic skin diseases constitute a diverse group of several hundred diseases that affect up to 2% of the population and include common disease such as psoriasis, atopic dermatitis, and wound…

Continue ReadingiPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa

RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency

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  • Post published:June 9, 2025
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Human embryonic stem cells (hESC) have the remarkable capacity to replicate indefinitely and differentiate into virtually any cell type in the human body. Maintaining this pluripotent cell state requires the…

Continue ReadingRNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency

WNT signaling and the control of cell fate decisions in human pluripotent stem cells.

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  • Post published:June 9, 2025
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With their ability to develop into virtually all mature cell types, human pluripotent stem cells (hPSC) represent a unique and powerful research tool to study the fundamental mechanisms regulating human…

Continue ReadingWNT signaling and the control of cell fate decisions in human pluripotent stem cells.

The stem cell microenvironment in the maintenance of pluripotency and reprogramming

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  • Post published:June 9, 2025
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Pluripotent stem cell research is just on the verge of beginning to fulfill its promise to revolutionize medicine. Whether they are derived from embryos, or from adult cells that have…

Continue ReadingThe stem cell microenvironment in the maintenance of pluripotency and reprogramming
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