Transcriptome Encyclopedia of Early Human Development.

Publication Year:

2016

Authors:

Anna Sahakyan, Kathrin Plath

PubMed ID:

27153491

Funding Grants:

Understanding the status of the X chromosomes in human ESCs and preimplantation embryos

Public Summary:

Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on mouse studies. Petropoulos et al. now provide an extensive transcriptome analysis of a large number of human pre-implantation embryos at single-cell resolution, revealing previously unrecognized features unique to early human development.

Scientific Abstract:

Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on mouse studies. Petropoulos et al. now provide an extensive transcriptome analysis of a large number of human pre-implantation embryos at single-cell resolution, revealing previously unrecognized features unique to early human development.