Network biology: A compass for stem-cell differentiation.
Publication Year:
2014
PubMed ID:
25254472
Funding Grants:
- TSRI Center for hESC Research
- Collaborative Laboratory for Human Embryonic Stem Cell Research at Sanford-Burnham Medical Research Institute
- The Stem Cell Matrix: a map of the molecular pathways that define pluripotent cells
- Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation
Public Summary:
We critically assess the value to regenerative medicine of transcriptional analysis, pointing out that directly reprogrammed (transdifferented) cells can sometimes be abnormal and express characteristics of more than one cell type.
