iPS cells: insights into basic biology.

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Public Summary:
This a review article where I propose that the process of iPS cell generation may provide important novel insights into basic biological processes, such regulation of gene activity during embryonic development or cellular transformation in cancer.
Scientific Abstract:
The discovery that adult somatic cells can be induced to become pluripotent by overexpression of a few key transcription factors provides an exciting new window into the basic biology of pluripotency and differentiation.