aSIRTing Control over Cancer Stem Cells.

Journal: 
Cancer Cell
Publication Year: 
2012
Authors: 
Takahiro Ito
Bryan Zimdahl
Tannishtha Reya
PubMed link: 
22340585
Public Summary: 
Scientific Abstract: 
Cancer stem cells lie at the root of chronic myelogenous leukemia (CML) and mediate its continued growth. Their resistance to current therapies results in an inability to eradicate the disease. In this issue of Cancer Cell, Li et al. identify SIRT1 as a new target for eliminating CML cancer stem cells.