Adult stem-like cells exclude "older" mitochondria.

Journal: 
Cell Metab
Publication Year: 
2015
Authors: 
Michael A Teitell
PubMed link: 
25955200
Public Summary: 
Asymmetric distribution of damaged cellular constituents may occur during mitosis, resulting in more and less pristine daughter cell pairs. In Science, Katajisto et al., (2015) report that mammary stem-like cells (SLCs) unequally apportion older mitochondria to post-division daughter cells, with the daughter containing younger mitochondria maintaining the SLC pool.
Scientific Abstract: 
Asymmetric distribution of damaged cellular constituents may occur during mitosis, resulting in more and less pristine daughter cell pairs. In Science, Katajisto et al., (2015) report that mammary stem-like cells (SLCs) unequally apportion older mitochondria to post-division daughter cells, with the daughter containing younger mitochondria maintaining the SLC pool.