Preclinical Development

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Objective

The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a diverse California and world.

CIRM’s Preclinical Development funding programs include complementary funding opportunities that support and accelerate preclinical development of stem cell-based and genetic therapies for diseases affecting Californians.

Explore Funding Opportunities

The RAPID application period opens in July and closes in September 2026. The Rare Disease Acceleration Through Platform Innovation and Delivery (RAPID) program advances the development and delivery of platform-based genetic therapies for Americans with rare diseases. Download the RAPID Program Request for Applications (RFA) for more details regarding award eligibility, review criteria, and application information. Visit the RAPID Awards page for more information about the RAPID awards, including deadlines, requirements, and FAQs.
The PDEV application opens in July/August 2026. The Preclinical Development (PDEV) program supports preclinical development of stem cell-based and genetic therapies that not only offer potential for transformative clinical impact but also meaningfully address current barriers to patient access. Download the PDEV Program Announcement (PA) for more details regarding award eligibility, review criteria, and application information. Visit the PDEV Awards page for more information about the PDEV awards, including deadlines, requirements, and FAQs.
The RAPID application period opens in July and closes in September 2026. The Rare Disease Acceleration Through Platform Innovation and Delivery (RAPID) program advances the development and delivery of platform-based genetic therapies for Americans with rare diseases. Download the RAPID Program Request for Applications (RFA) for more details regarding award eligibility, review criteria, and application information. Visit the RAPID Awards page for more information about the RAPID awards, including deadlines, requirements, and FAQs.
The PDEV application opens in July/August 2026. The Preclinical Development (PDEV) program supports preclinical development of stem cell-based and genetic therapies that not only offer potential for transformative clinical impact but also meaningfully address current barriers to patient access. Download the PDEV Program Announcement (PA) for more details regarding award eligibility, review criteria, and application information. Visit the PDEV Awards page for more information about the PDEV awards, including deadlines, requirements, and FAQs.

To Submit an Application:

Log in with your existing CIRM Username and Password. If you do not have a Username, click on the “New User” link and follow the instructions to Create a CIRM Username and password.

Select the tab labeled “Open Programs” under the section labeled “RFAs and Programs Open for Applications,” click on the “Start a Grant Application” link for your selected program.

Click on the appropriate link and follow the posted instructions. Proposal templates can be located and submitted under the “Uploads” section.

Click on the “Done with Application” button. The “Done with Application” button will be enabled when all the mandatory sections have been completed. Please note that once this has been selected, you will no longer be able to make changes to your application.

Select the tab labeled “Your Applications” and check the table under the section labeled “Your Submitted Applications.” You will see your application number and project title listed once the submission process has been completed.