Global profiling of miRNA-based gene activation to enable a new category of genetic medicine

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Grant Award Details

Grant Number:
DISC0-17998
Investigator(s):
Name:
Institution:
Type:
PI

Award Value:
$2,997,574
Status:
Pre-Active

Grant Application Details

Application Title:

Global profiling of miRNA-based gene activation to enable a new category of genetic medicine

Public Abstract:
Research Objective

The proposed research will address key knowledge gaps in small activating RNAs (saRNAs) and could overcome bottlenecks limiting the broader adoption of this technology for regenerative medicine

Impact

If successful, the proposed technology could activate the expression of many different genes throughout the genome, with applications to both rare disease and highly prevalent conditions.