The goals for establishing the Lundquist Institute CIRM training program were threefold: 1) to create a stem cell-focused program at TLI that will enable to recruit and train researchers in stem cell biology and regenerative medicine, its translational significance, the underlying ethical considerations, “bench-to-bedside” translation, and commercialization strategies; 2) to educate the public, with a specific focus on South Bay, on the biology and ethics of stem cell research and keep the community updated on the technological advances in the field; and 3) to retain the trained stem cell researchers by providing access to the latest emerging companies based locally at TLI.
In this second reporting period, in line with our first goal, the TLI CIRM training program has recruited and supported nine postdoctoral fellows and 4 graduate students. The scientific projects span a wide array of stem cell-related projects involving several organ systems which primarily include the immune system, the developing lung, brain, pancreas, etc. The scope of these projects’ include disease modeling, gene editing approaches, as well as gene and cell therapy. The trainees continue to be mentored by world renowned experts in developmental biology and stem cell research who have expertise in germ cells, human embryonic stem cell (hESC), and induced pluripotent stem cell (iPSC) culture and differentiation.
A set of courses and training modules took place in this period. Didactic courses in biostatistics, responsible conduct of research as well as technology transfer and commercialization class, and basics in stem cell biology class, were conducted. Mentoring and career development events were also held.
In line with our second CIRM program goal, during this period of the training program, CIRM trainees participated in training and outreach opportunities through the high school summer program as well as the little Einstein’s program initiated by the Lundquist Institute. In addition, they participated in a Mini Medical school initiative, where they introduced stem cells and stem cell research to elementary school students in TLI’s neighborhoods.
Many trainees attended national and international meetings where they presented their work and earned awards which included three prestigious awards from the American Thoracic Society and the American Physiological society, highlighting the quality of their research and recognition in the field. The trainees also attended the President’s Lecture Series, Institute of Women and Children’ Health Institute Within the Institute monthly lectures, featuring several renowned stem cell scientists. Furthermore, the trainees presented their work in progress at the bi-monthly research in progress forum and The Lundquist Institute (TLI) poster Day in October 2023. A total of three original supported by CIRM were published. In addition, we are partnering with other CIRM EDUC4 programs (e.g. CHLA), to expand the access of the trainees to scientific lectures and events. Our goal is to eventually lead CIRM fellows to achieve their goals and become significant players in stem cell research and regenerative medicine.
