The CIRM Bridges program in stem cell research and therapy has allowed selected students from underrepresented and underserved communities the opportunity to experience and participate in world class research in stem cell biology and translational medicine. In the course of their 10-month internships in academic research laboratories, students worked alongside scientists and technicians learning how to design a research experiment and see a project through to completion, ultimately pulling together their results for oral presentations and a scientific poster. Throughout their internships, students hone their laboratory and critical thinking skills, work with advanced technologies not available in their college courses and, through daily interactions with graduate students, postdoctoral fellows and other scientists, clarify future career pathways for themselves. Importantly, the interns develop confidence in their ability to contribute to the exciting fields of medical research and innovative gene-based therapies. Other opportunities afforded the interns include attending stem cell workshops and symposia pertinent to their research, and seminars that address the ethical and legal issues associated with stem cell therapies. This year the interns will attend the Society for the Advancement of Chicanos/Hispanics and Native Americans in Science (SACNAS) in Portland, Oregon this fall. An integral part of the internship involves communicating with patients and patient advocates. Interns hear first hand from patients and their families what it is like to struggle daily with debilitating conditions such as Alzheimer’s, Parkinson’s, cystic fibrosis, and serious neurological injuries that result in paralysis. Witnessing personal stories and connecting with patients with genetic-based conditions deepens their appreciation for the need for translational research and gene-based therapies. CIRM interns also have the opportunity to share their experiences with other students through formal presentations of their research in classes, informal meetings with biology and biotechnology students, and with the college’s public information officer who will ensure that the opportunities and experiences of the CIRM interns are heard by a broader audience and members of the community.