CIRM Center of Excellence at Buck Institute for Age Research

CIRM Center of Excellence at Buck Institute for Age Research


Buck Institute for Age Research
Major Facilities: FA1-00600-1
Status: Active
$20500000.00

The Major Facilities Awards were intended to construct state-of-the-art stem cell facilities that are free of federal funds. The $270,946,930 in CIRM funding for 12 buildings leveraged more than $800 million in private and institutional funds. The buildings had the ambitious requirement of being completed within two-years. You can learn more about these facilities by reading the RFA, reading the press release, or watching this video about the value of the buildings.

Public Abstract (provided by applicant)

FACILITY The Buck Institute for Age Research proposes to develop a CIRM Major Facility to investigate the role of stem cells in aging and in the pathogenesis, diagnosis and treatment of age-related disease. A new building devoted to human embryonic stem cell (hESC) research will be constructed adjacent to space earmarked for our CIRM Shared Research Laboratory and Stem Cell Techniques Course. The project will be expedited by our recent experience completing a NCRR Center for Integrative Studies of Aging on time and within budget. The CIRM Major Facility will contain laboratories for 12 principal investigators (PIs) and space for cell culture, shared equipment and research cores. The cores will be devoted to cell sorting, imaging, genomics, proteomics, high-throughput screening (HTS), electrophysiology and bioinformatics/statistics, and will be fiscally separate satellites of existing, NIH-supported cores. The CIRM Major Facility will be closely integrated with our CIRM Shared Research Laboratory, which will house another 4 PIs. Core support within the Institute but outside the Facility will include the vivarium and the transgenic and animal-behavior cores. PROGRAM The Buck Institutes

Statement of benefit to California (provided by applicant)

The 2000 US Census showed that 10.6% of Californians were aged 65 or older and 1.3% were 85 or older. According to a 2003 special report from the California Policy Research Center on "The Growth and Aging of California