Download Unit 1

Unit 1: Embryonic Stem Cells, Natural and In Vitro Fertilization, Preimplantation Genetic Diagnosis

By Kathy Keeran, Lonnie Simonson, and Laurel Barchas

See all units

Help us improve our curriculum
Sign up to participate in our survey

Suggested time frame: One to six class periods

Course level: Beginning Biology, review for AP biology, community college beginning biology classes

Inquiry teaching: Read how to modify the curriculum for inquiry teaching



Brief outline of Unit 1 with download links

I. Invitation and pre-assessment

1. Writing activity
2. My Sister’s Keeper, Octomom

II. Exploration

A. Natural fertilization and development of embryonic stem cell lines; origins of totipotent and pluripotent stem cells

1. Lecture with power point- stages of embryonic and fetal development

i. Download Appendix A: Natural Fertilization presentation [power point]
ii. Download Appendix A: Unit One Natural Fertilization student worksheet [pdf]
iii. Download Appendix A: Unit One Natural Fertilization teacher version [pdf]

2. Animation of natural fertilization

3. Lab- sea urchin development

i. Download Appendix B: sea urchin microscope labgraphic organizer [pdf]

4. Embryonic development and location of stages and sites at which totipotent and pluripotent stem cells occur.

i. Download Appendix C: Playdough-modeling Activity [pdf]

B. In Vitro Fertilization and what happens to un-implanted embryos

1. Video clips, animations and discussion of in vitro fertilization: Northern Calif. Fertility Medical Center, Howard Hughes Medical Institute

i. Download Appendix D: student graphic organizer [pdf]
ii. Download Appendix D:teacher answer sheet [pdf]

2. Animation of intra-cytoplasmic sperm injection- Schering-Plough production of ICSI procedure

C. Pre-implantation genetic diagnosis (PGD) techniques, uses and ethical considerations

1. Animation and discussion of stem cell lines and ability of stem cells to differentiate; medical uses
2. Jigsaw study of scientific paper summaries; includes jigsaw instructions

i. Download Appendix E: jigsaw general instructions [pdf]
ii. Download Appendix E: Summaries of research papers [pdf]

III. Application

1. Discussion of ethics of PGD following jigsaw
2. Ranking exercise of policy options with graphic organizer

i. Download Appendix F: policy options ranking sheet [pdf]

IV. Assessment

1. Post- assessment thought questions

i. Download Appendix G: Unit Assessment [pdf]








© 2013 California Institute for Regenerative Medicine