iPS cells: insights into basic biology.

Journal: 
Cell
Publication Year: 
2009
Authors: 
Miguel Ramalho-Santos
Public Summary: 
This a review article where I propose that the process of iPS cell generation may provide important novel insights into basic biological processes, such regulation of gene activity during embryonic development or cellular transformation in cancer.
Scientific Abstract: 
The discovery that adult somatic cells can be induced to become pluripotent by overexpression of a few key transcription factors provides an exciting new window into the basic biology of pluripotency and differentiation.

© 2013 California Institute for Regenerative Medicine