Before a new therapy is widely available in doctors' offices, it goes through several rounds of carefully regulated testing in people. These happen in three stages:
- Phase 1 trials include a very small number of people and are primarily intended to test whether the proposed therapy is safe.
- Phase 2 trials include slightly more people and are intended to verify that the therapy is safe, and to start looking into whether it is effective at treating the disease or condition.
- Phase 3 trials include large numbers of people and are intended to test whether the therapy treats the disease or condition.
All clinical trials carried out in the United States are required to be listed on the clinicaltrials.gov website. Those trials being carried out in other countries won't always have additional trial details available through that site.
CIRM-Funded Clinical Trials
These clinical trials are being directly funded by grants from CIRM.
|Capricor||Heart disease||Disease Team||Phase 1/2 NCT01458405|
|Calimmune||HIV/AIDS||Disease Team||Phase 1/2 NCT01734850|
|City of Hope
|UC Davis||Huntington's disease||Disease Team||Observational
|UCLA||Solid tumors||Disease Team||Phase 1|
|UCSD||Leukemia||Disease Team||Phase 1|
|UCLA||Sickle cell disease||Disease Team||Phase 1 (not yet enrolling)|
|Stanford||Solid tumors||Disease Team||Phase 1|
|Viacyte||Diabetes||Strategic Partnership I||Phase 1
|Asterias Biotherapeutics||Spinal Cord Injury||Strategic Partnership III Track A||Phase 1/2a (not yet enrolling)
|USC||Blindness||Disease Team||Phase 1 (not yet enrolling)|
|Geron||Spinal cord injury||Targeted Clinical Development||Phase 1
These clinical trials are based on discoveries made by our grantees when they were carrying out CIRM-funded research.
|Grantees||Trial sponsor||Disease||Supporting Grant||Trial details|
|Mark Marsala||Neuralstem||Spinal Cord Injury||Comprehensive Grant||Phase 1 NCT01772810|
|Catriona Jamieson||Sanofi||Polycythemia vera||Training
|Joel Gottesfeld||Repligen, Corp||Ataxia||Basic Biology||Phase 1 Italy|
|Jonsson Comprehensive Cancer Center||Metastatic melanoma||Phase 2 NCT00910650|
|Stem Cells, Inc||Spinal cord injury||Training||Phase 1/2