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Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors.

MicroRNAs are required for maintenance of pluripotency as well as differentiation, but since more microRNAs have been computationally predicted in genome than have been found, there are likely to be…

Continue Reading Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors.

Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines.

The self-renewal and differentiation potential of human embryonic stem cells (hESCs) suggests that hESCs could be used for regenerative medicine, especially for restoring neuronal functions in brain diseases. However, the…

Continue Reading Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines.

Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells.

Continue Reading Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells.

Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.

Our study has revealed a function of protein phosphatase 4 in transcriptional repression that contributes to silencing of key development-related genes in pluripotent embryonic stem cells.

Continue Reading Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.

A DNA repair complex functions as an oct4/sox2 coactivator in embryonic stem cells.

The transcriptional activators Oct4, Sox2, and Nanog cooperate with a wide array of cofactors to orchestrate an embryonic stem (ES) cell-specific gene expression program that forms the molecular basis of…

Continue Reading A DNA repair complex functions as an oct4/sox2 coactivator in embryonic stem cells.

Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence.

Continue Reading Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence.

Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.

Continue Reading Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.

Culturing Human Embryonic Stem Cells in Feeder-Free Conditions

Continue Reading Culturing Human Embryonic Stem Cells in Feeder-Free Conditions
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