The MLLgnant consequences of reverting to an embryonic transcriptional program.

Cell Stem Cell
Publication Year: 
Catriona Jamieson
Public Summary: 
Scientific Abstract: 
In this issue of Cell Stem Cell, Somervaille et al. (2009) have demonstrated convincingly that reversion to an embryonic transcriptional program through defective MLL gene expression contributes to the generation of myeloid leukemia stem cells.

© 2013 California Institute for Regenerative Medicine