The MLLgnant consequences of reverting to an embryonic transcriptional program.

Journal: 
Cell Stem Cell
Publication Year: 
2009
Authors: 
Catriona Jamieson
PubMed link: 
19200795
Public Summary: 
Scientific Abstract: 
In this issue of Cell Stem Cell, Somervaille et al. (2009) have demonstrated convincingly that reversion to an embryonic transcriptional program through defective MLL gene expression contributes to the generation of myeloid leukemia stem cells.