Transcriptome Encyclopedia of Early Human Development.

Journal: 
Cell
Publication Year: 
2016
Authors: 
Anna Sahakyan
Kathrin Plath
PubMed link: 
27153491
Public Summary: 
Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on mouse studies. Petropoulos et al. now provide an extensive transcriptome analysis of a large number of human pre-implantation embryos at single-cell resolution, revealing previously unrecognized features unique to early human development.
Scientific Abstract: 
Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on mouse studies. Petropoulos et al. now provide an extensive transcriptome analysis of a large number of human pre-implantation embryos at single-cell resolution, revealing previously unrecognized features unique to early human development.