All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $2,760,540
University of California, Irvine Craig Walsh Early Translational III Multiple Sclerosis therapy: Human Pluripotent Stem Cell-Derived Neural Progenitor Cells $4,590,219
University of California, Santa Cruz Bin Chen SEED Grant In vitro differentiation of hESCs into corticospinal motor neurons $465,624
City of Hope Larry Couture Tools and Technologies I Development of Suspension Adaptation, Scale-up cGMP Banking and Cell Characterization Technologies for hESC Lines $882,929
University of California, San Diego Charles King Basic Biology III Biological relevance of microRNAs in hESC differentiation to endocrine pancreas $1,313,649
City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
University of California, Berkeley Lin He New Faculty II The roles of non-coding RNAs in the self-renewal and differentiation of pluripotent stem cells $1,406,823
City of Hope John Zaia Strategic Partnership III Track A A Phase I, Open-Label Study to Assess the Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells with Escalating Doses of Busulfan in HIV-1 (R5) Infected Subjects with Suboptim $5,583,438
Stanford University Helen Blau Basic Biology V Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging $1,175,357
University of California, San Diego Mark Tuszynski Early Translational III Functional Neural Relay Formation by Human Neural Stem Cell Grafting in Spinal Cord Injury $3,973,514
Gladstone Institutes Warner Greene SEED Grant The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $717,363
Scripps Research Institute Nicholas Gascoigne Transplantation Immunology Role of Innate Immunity in hematopoeitic stem cell-mediated allograft tolerance $1,705,554
University of California, Santa Cruz David Haussler Research Training II CIRM Training Program in Systems Biology of Stem cells $4,397,002
Stanford University Michele Calos Early Translational II Stem Cell Therapy for Duchenne Muscular Dystrophy $2,267,261
University of California, Davis Alice Tarantal Comprehensive Grant Preclinical Model for Labeling, Transplant, and In Vivo Imaging of Differentiated Human Embryonic Stem Cells $2,166,757
University of California, Los Angeles John Adams Alpha Stem Cell Clinics Alpha Stem Cell Clinic (ASCC) Consortium $8,000,000
Palo Alto Institute for Research and Education Thomas Rando Basic Biology V Molecular regulation of stem cell potency $966,510
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
University of California, Santa Cruz David Feldheim SEED Grant Assessing the role of Eph/ephrin signaling in hESC growth and differentiation $474,161
Stanford University Anne Brunet New Faculty I Molecular mechanisms involved in adult neural stem cell maintenance $2,348,435
California State University, Northridge Cindy Malone Bridges Bridges to Stem Cell Research $3,905,951
University of California, San Diego Lawrence Goldstein Disease Team Research I Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $5,694,308
University of California, San Diego Martin Marsala Comprehensive Grant Spinal ischemic paraplegia: modulation by human embryonic stem cell implant $2,356,090
University of Southern California Chrysostomos Nikias Major Facilities Broad CIRM Facility at USC $26,972,500
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
Gladstone Institutes Yadong Huang New Faculty II Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo $2,757,303
University of California, San Francisco Ann Zovein New Faculty Physician Scientist Human endothelial reprogramming for hematopoietic stem cell therapy. $2,319,784
University of Southern California Songtao Shi New Faculty I Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells $3,242,651
University of California, Davis Mehrdad Abedi Disease Team Therapy Planning I RUNNING TITLE: Stem Cell Gene Therapy for HIV in AIDS Lymphoma Patients $66,880
Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $778,859
University of California, Davis Laura Marcu Tools and Technologies III Multimodal platform combining optical and ultrasonic technologies for in vivo nondestructive evaluation of engineered vascular tissue constructs $1,834,474
University of California, Davis Alice Tarantal Early Translational I In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies $3,143,392
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $12,131
University of Southern California Roberta Brinton Creativity Awards CIRM STAR High School Summer Research and Creativity Program $271,160
Sanford-Burnham Medical Research Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $1,020,815
University of California, Los Angeles Martin Martin Tools and Technologies II Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
University of California, Los Angeles Owen Witte Training Grant I-1 CIRM Type I Comprehensive Training Program $3,660,398
University of California, San Francisco Su Guo SEED Grant Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons $542,619
Scripps Health Darryl D'Lima Preclinical Development Awards Embryonic Stem Cell-Derived Chondroprogenitor Cells to Repair Osteochondral Defects $7,660,211
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $1,638,357
University of California, Los Angeles Gay Crooks Basic Biology III Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,252,857
Stanford University Steven Artandi Basic Biology II Self-renewal and senescence in iPS cells derived from patients with a stem cell disease $931,285
Scripps Research Institute Jeanne Loring Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $1,361,825
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells $4,179,598
University of California, San Diego Eugene Yeo Early Translational III Molecules to Correct Aberrant RNA Signature in Human Diseased Neurons $1,532,323
University of California, San Francisco Thea Tlsty SEED Grant Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells. $614,784
University of California, San Diego Steve Dowdy Tools and Technologies I TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $720,000
Stanford University Sean Wu Basic Biology III Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells $1,260,537
Buck Institute for Age Research Xianmin Zeng Early Translational II Banking transplant ready dopaminergic neurons using a scalable process $4,983,013
University of California, San Diego Mana Parast New Faculty II Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,077,918
University of California, Berkeley Xavier Darzacq Research Leadership Single Molecule Biophysics and Biology of Cellular Identity $4,255,167
Salk Institute for Biological Studies Ronald Evans Basic Biology V Metabolically-driven epigenetic changes in iPSC reprogramming $1,491,900
Salk Institute for Biological Studies David Schubert Early Translational III Stem cell based small molecule therapy for Alzheimer's disease $1,673,757
Stanford University Phillip Yang SEED Grant In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $629,952
Palo Alto Institute for Research and Education Husein Hadeiba Transplantation Immunology Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation $733,061
Salk Institute for Biological Studies Juan Carlos Izpisua Belmonte Research Training II Training in the Biology of Human Embryonic Stem Cells and Emerging Technologies II $2,886,221
University of California, Irvine leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,527,011
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,467,200
City of Hope John Zaia Alpha Stem Cell Clinics The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,000,000
University of California, Merced Kara McCloskey Basic Biology V Directed Differentiation of Specialized Endothelial Cells $476,052
Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,482,025
University of California, Los Angeles William Lowry SEED Grant Modeling Human Embryonic Development with Human Embryonic Stem Cells $528,096
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $2,985,894
California State University, Sacramento Jane Bruner Bridges Strengthening the Pipeline of Masters-level Scientific and Laboratory Personnel in Stem Cell Research $3,057,754
University of California, Irvine Leslie Thompson New Cell Lines New Cell Lines for Huntington's Disease $1,302,526
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $2,832,000
University of California, San Francisco Jeffrey Bluestone Disease Team Planning A CIRM Disease Team for the Treatment and Cure of Diabetes $55,000
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
University of California, San Diego Benjamin Yu New Faculty II Regulation of Adult Stem Cell Proliferation by RAS and Cell-Permeable Proteins $3,017,978
Stanford University Michelle Monje New Faculty Physician Scientist White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain” $2,800,536
University of California, San Diego David Traver New Faculty I Genetic dissection of mesodermal commitment to the hematopoietic fates. $2,150,620
StemCells, Inc. Alexandra Capela Disease Team Therapy Planning I Neuroprotection to treat Alzheimer's: a new paradigm using human central nervous system cells $90,101
University of California, San Diego Sylvia Evans SEED Grant Specification of Ventricular Myocyte and Pacemaker Lineages Utilizing Human Embryonic Stem Cells $585,600
Stanford University Fan Yang Tools and Technologies III Injectable Macroporous Matrices to Enhance Stem Cell Engraftment and Survival $1,438,200
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
Sanford-Burnham Medical Research Institute Mark Mercola Disease Team Planning "Stem Cell Therapies for Heart Failure" $44,450
University of California, Davis Emanual Maverakis New Faculty Physician Scientist Tunable hydrogels for therapeutic delivery of multipotent stem cells. $2,772,000
Stanford University Michele Calos Early Translational IV Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B $1,876,253
Stanford University Brian Rutt Tools and Technologies II Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters $1,833,348
University of California, Davis Frederick Meyers Training Grant I-1 Stem Cell Research Training Grant $1,780,859
University of Southern California David Hinton SEED Grant Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. $651,607
Stanford University Matthew Porteus Preclinical Development Awards Pre-clinical development of gene correction therapy of hematopoietic stem cells for SCID-X1 $874,877
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,737,133
Gladstone Institutes Deepak Srivastava Basic Biology III Mechanisms of Direct Cardiac Reprogramming $1,572,380
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology II Endothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes $1,587,610
Gladstone Institutes Deepak Srivastava Shared Labs CIRM Shared Human Embryonic Stem Cell Core Laboratory $842,672
Stanford University Irving Weissman Disease Team Therapy Development III Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors $6,505,568
Stanford University Helen Blau Early Translational III Local Delivery of Rejuvenated Old Muscle Stem Cells to Increase Strength in Aged Patients $1,825,920
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $529,762
University of California, Irvine Lisa Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $861,122
Scripps Research Institute Joel Gottesfeld Basic Biology III Triplet Repeat Instability in Human iPSCs $1,705,494
University of California, Davis Mark Zern Early Translational II Liver Cell Transplantation $4,212,621
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,075,251
Gladstone Institutes Todd McDevitt Research Leadership Engineering microscale tissue constructs from human pluripotent stem cells $6,368,285
University of California, Los Angeles Bennett Novitch Basic Biology V In vitro modeling of human motor neuron disease $1,148,758
Stanford University Judith Shizuru Disease Team Therapy Development - Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $19,068,382
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $587,591
Escape Therapeutics, Inc Basil Hantash Transplantation Immunology Development of an immune tolerant hESC source for allogeneic cell therapy applications $1,453,040
Stanford University Theo Palmer Research Training II CIRM Training Program $7,475,333
Salk Institute for Biological Studies Fred Gage Early Translational II Crosstalk: Inflammation in Parkinson’s disease (PD) in a humanized in vitro model $2,472,839

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