All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
University of California, Berkeley Dr. Kevin E. Healy Quest – Discovery Stage Research Projects Human Cardiac Chip for Assessment of Proarrhythmic Risk $899,581
University of California, San Francisco Dr. Holger F Willenbring Quest – Discovery Stage Research Projects Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis $1,638,389
Scaled Biolabs Inc. Dr Justin Cooper-White Quest – Discovery Stage Research Projects A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs $657,528
City of Hope, Beckman Research Institute Markus Müschen Quest – Discovery Stage Research Projects Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,183,223
University of California, San Diego Professor Alysson R Muotri Quest – Discovery Stage Research Projects A treatment for Zika virus infection and neuroprotection efficacy $1,924,524
Stanford University Dr. Matthew H Porteus Quest – Discovery Stage Research Projects Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells $1,968,456
University of California, San Francisco Dr. Julie B Sneddon Quest – Discovery Stage Research Projects Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells $2,006,076
University of California, Los Angeles Dr. John P Chute Quest – Discovery Stage Research Projects Protein tyrosine phosphatase – sigma inhibitors for hematopoietic regeneration $2,115,735
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Targeted off-the-shelf immunotherapy to treat refractory cancers $1,936,936
Parkinson’s Institute Dr. Birgitt Schuele Quest – Discovery Stage Research Projects CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease $1,288,415
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Direct Cardiac Reprogramming for Regenerative Medicine $2,392,157
University of California, Irvine Leslie M Thompson Quest – Discovery Stage Research Projects hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
Stanford University Dr. Roel Nusse Quest – Discovery Stage Research Projects Preclinical development of human hepatocyte progenitor cells for cell therapy $1,651,211
University of California, San Francisco Dr. Tejal Ashwin Desai Quest – Discovery Stage Research Projects Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells $1,092,063
Stanford University Dr. Rosa Bacchetta Quest – Discovery Stage Research Projects GENE EDITING FOR FOXP3 IN HUMAN HSC $984,228
California Institute of Technology Dr. David Baltimore Quest – Discovery Stage Research Projects Immunotherapy for HIV infection using engineered hematopoietic stem/progenitor cells $1,569,193
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Use of Human iPSC-derived Endothelial Cells for Calcific Aortic Valve Disease Therapeutics $2,400,048
Scripps Research Institute Dr. Jeanne F Loring Quest – Discovery Stage Research Projects Autologous cell therapy for Parkinson’s disease using iPSC-derived DA neurons $2,299,786
University of California, Davis Dr. David J Segal PhD Quest – Discovery Stage Research Projects MSC delivery of an artificial transcription factor to the brain as a treatment for Angelman Syndrome $1,055,319
University of California, Berkeley David V. Schaffer Quest – Discovery Stage Research Projects Scalable, Defined Production of Oligodendrocyte Precursor Cells to Treat Neural Disease and Injury $1,627,099
Stanford University Professor Hiromitsu Nakauchi Quest – Discovery Stage Research Projects Novel Rejuvenated T Cell Immunotherapy for Lung Cancer $1,968,456
University of California, Los Angeles Dr. April Pyle Ph.D. Quest – Discovery Stage Research Projects CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells $2,150,400
University of California, San Diego Dr. Karl J. Wahlin Inception – Discovery Stage Research Projects An IPSC cell based model of macular degeneration for drug discovery. $232,200
University of California, Los Angeles Alireza Moshaverinia Inception – Discovery Stage Research Projects Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
Zenobia Therapeutics Vicki Nienaber Inception – Discovery Stage Research Projects A new phenotypic screening platform that identifies biologically-relevant targets and lead compounds for the treatment of Parkinson’s disease $112,500
Cedars-Sinai Medical Center Dmitriy Sheyn Inception – Discovery Stage Research Projects IVD rejuvenation using iPSC-derived notochordal cells $241,992
Loma Linda University Dr. David J Baylink Inception – Discovery Stage Research Projects Bone Marrow Targeting of Hematopoietic Stem Cells Engineered to Overexpress 25-OH-VD3 1-α-hydroxylase for Acute Myeloid Leukemia Therapy $178,967
Palo Alto Veterans Institute for Research Dr. Ngan F Huang Inception – Discovery Stage Research Projects iPSC-Derived Smooth Muscle Progenitors for Treatment of Abdominal Aortic Aneurysm $172,621
University of California, Davis Dr. Alice F Tarantal Inception – Discovery Stage Research Projects Enhanced Branching Morphogenesis and Pluripotent Cell Lineage Differentiation for Pediatric Regenerative Therapies $235,800
Loma Linda University Julia J. Unternaehrer-Hamm Inception – Discovery Stage Research Projects Targeting cancer stem cells with nanoparticle RNAi delivery to prevent recurrence and metastasis of ovarian cancer $172,870
Human BioMolecular Research Institute Dr. John R Cashman Inception – Discovery Stage Research Projects Human Pancreatic Cancer Stem Cells: Developing a Novel Drug for Cancer Eradication $303,785
Stanford University Professor Hiromitsu Nakauchi Inception – Discovery Stage Research Projects Optimizing self-renewal signaling kinetics to stabilize ex vivo hematopoietic stem cell expansion $210,906
University of California, San Diego Gerald P Morris Inception – Discovery Stage Research Projects Identification of antigenic neo-epitopes from in vitro reprogrammed human tissue precursors for regenerative therapy $193,500
University of California, Davis Alyssa Panitch PhD Inception – Discovery Stage Research Projects Development of treatments to improve healing of ischemic wounds $235,099
Stanford University Guillem Pratx Inception – Discovery Stage Research Projects Novel metabolic labeling method for tracking stem cells to irradiated salivary glands using PET $229,227
University of California, San Francisco Semil P Choksi Inception – Discovery Stage Research Projects Generation of human airway stem cells by direct transcriptional reprogramming for disease modeling and regeneration $238,408
University of California, Irvine Janet E Baulch Inception – Discovery Stage Research Projects An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology $157,650
University of California, San Diego Dr. Tannishtha Reya Inception – Discovery Stage Research Projects Reprogramming human stem cells for blood cell generation $210,060
Stanford University Dr. Helen M Blau Inception – Discovery Stage Research Projects Prodrug innovation to target muscle stem cells and enhance muscle regeneration $235,834
Sanford Burnham Prebys Medical Discovery Institute Dr Alessandra Sacco Inception – Discovery Stage Research Projects Generation of expandable, self-renewing muscle stem cells for Duchenne Muscular Dystrophy $252,000
University of California, San Francisco Sonja Schrepfer Inception – Discovery Stage Research Projects Hypo-immunogenic cardiac patches for myocardial regeneration $235,818
University of Southern California Biju B. Thomas Inception – Discovery Stage Research Projects A Novel Tissue Engineering Technique to Repair Degenerated Retina $215,133
Children’s Hospital of Los Angeles Dr. Senta Georgia Inception – Discovery Stage Research Projects Developing a personalized approach to beta cell replacement for patients with a genetic form of diabetes $179,995
Vitalant Research Institute Dr. Marcus Oliver Muench Inception – Discovery Stage Research Projects Modulating Liver Sinusoidal Endothelial Cell Permeability to Enhance Engraftment of Endothelial Cell Progenitors for the Treatment of Hemophilia A $180,000
Stanford University Jeffrey L Goldberg Inception – Discovery Stage Research Projects Embryonic Stem Cells for Corneal Endothelial Degeneration $235,836
University of California, Los Angeles Dr. Owen N Witte M.D. Inception – Discovery Stage Research Projects Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
University of California, San Diego Professor Alysson R Muotri Inception – Discovery Stage Research Projects Reverse transcriptase inhibitors as a novel therapeutic approach for neurological autoimmune disorders $210,060
University of California, Los Angeles Dr. April Pyle Ph.D. Inception – Discovery Stage Research Projects Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
University of California, Los Angeles Dr. Bennett G Novitch Ph.D. Inception – Discovery Stage Research Projects Organoid Modeling of Human Cortical Microcircuits $208,916
Cedars-Sinai Medical Center Professor Clive Niels Svendsen Inception – Discovery Stage Research Projects Blood Brain Barrier (BBB)-on-Chip: Development and validation of a novel iPS-based microfluidic model of the human BBB $241,992
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