All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Antoni Ribas Disease Team Therapy Development - Research Genetic Re-programming of Stem Cells to Fight Cancer $19,875,776
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $12,131
Gladstone Institutes Robert Mahley Research Training II CIRM Scholars Program $4,945,955
Numerate, Inc. John Griffin Early Translational IV Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin $520,015
Stanford University Anne Brunet New Faculty I Molecular mechanisms involved in adult neural stem cell maintenance $2,348,435
University of California, Irvine Brian Cummings SEED Grant The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $595,345
University of California, San Diego Martin Marsala Comprehensive Grant Spinal ischemic paraplegia: modulation by human embryonic stem cell implant $2,356,090
University of California, San Diego Dennis Carson Disease Team Research I Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT) $19,999,826
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
University of California, San Francisco Andrew Leavitt Tools and Technologies III Small molecule tools and scale-up technologies to expand human umbilical cord blood stem and progenitor cells for clinical and research use $1,416,600
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $1,976,931
California State University, San Marcos Bianca Mothe Bridges CIRM Bridges to the Stem Cell Research Training Grant $4,114,712
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $2,760,540
University of Southern California Songtao Shi New Faculty I Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells $3,242,651
Stanford University Mark Kay SEED Grant Novel vectors for gene transfer into human ES cells $574,737
University of California, Davis Alice Tarantal Early Translational I In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies $3,143,392
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
Stanford University Julie Baker New Cell Lines Derivation of hESC Lines with Disease Lesions $1,404,725
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
California Institute for Biomedical Research Peter Schultz Late Stage Preclinical Projects Development of a Chondrogenic Drug Candidate Targeting Resident Mesenchymal Stem Cells for the Treatment of Osteoarthritis $1,667,832
University of California, Berkeley Xavier Darzacq Research Leadership Single Molecule Biophysics and Biology of Cellular Identity $4,255,167
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
Salk Institute for Biological Studies Ronald Evans Basic Biology V Metabolically-driven epigenetic changes in iPSC reprogramming $1,491,900
University of California, Los Angeles Martin Martin Tools and Technologies II Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $1,638,357
Stanford University Krishna Shenoy SEED Grant Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium $572,891
University of California, Davis Min Zhao Basic Biology I Directing migration of human stem cells with electric fields $816,228
City of Hope John Zaia Alpha Stem Cell Clinics The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,000,000
University of California, Irvine Peter Bryant Training Grant I-1 Stem Cell Research Training Grant $1,935,487
University of California, Merced Kara McCloskey Basic Biology V Directed Differentiation of Specialized Endothelial Cells $476,052
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of California, San Diego Steve Dowdy Tools and Technologies I TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $720,000
University of California, Riverside Frank Sauer SEED Grant Non-coding RNA as tool for the active control of stem cell differentiation $571,650
University of California, San Diego Mana Parast New Faculty II Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,077,918
Stanford University Garry Nolan Basic Biology II Kinase signaling analysis of iPS cell reprogramming and differentiation $1,343,100
University of California, San Diego Eric Adler Early Translational III Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
University of California, San Francisco Jeffrey Bluestone Disease Team Planning A CIRM Disease Team for the Treatment and Cure of Diabetes $55,000
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
Stanford University Michelle Monje New Faculty Physician Scientist White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain” $2,800,536
Palo Alto Institute for Research and Education Husein Hadeiba Transplantation Immunology Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation $733,061
Salk Institute for Biological Studies Beverly Emerson SEED Grant Regulation of Specific Chromosomal Boundary Elements by CTCF Protein Complexes in Human Embryonic Stem Cells $647,343
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,467,200
University of California, San Diego Catriona Jamieson Early Translational II Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy $3,103,041
University of California, Davis John Laird Disease Team Therapy Development - Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $3,728,384
Sanford-Burnham Medical Research Institute Mark Mercola Disease Team Planning "Stem Cell Therapies for Heart Failure" $44,450
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,045
Sanford-Burnham Medical Research Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $1,020,815
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $2,985,894
Sanford-Burnham Medical Research Institute Hudson Freeze SEED Grant Role of Glycans in Human Embryonic Stem Cell Conversion to Neural Precursor Cells $708,000
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $2,832,000
Stanford University Alfred Lane Disease Team Research I iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa $11,039,208
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
Stanford University Joseph Wu Tools and Technologies III Advanced animal model for predictive preclinical testing of engineered cardiac autografts and allografts $1,689,744
Scripps Research Institute Jeanne Loring Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $1,361,825
City College Of San Francisco Carin Zimmerman Bridges Stem Cell Training Enhancement Program $2,704,836
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells $4,179,598
University of California, San Diego David Traver New Faculty I Genetic dissection of mesodermal commitment to the hematopoietic fates. $2,150,620
Stanford University Julien Sage SEED Grant Functions of RB family proteins in human embryonic stem cells $498,609
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,266,134
Stanford University Michele Calos New Cell Lines Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses $1,406,875
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
University of California, Los Angeles John Chute Research Leadership Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors $5,174,715
Gladstone Institutes Todd McDevitt Research Leadership Engineering microscale tissue constructs from human pluripotent stem cells $6,368,285
Sanford-Burnham Medical Research Institute Stuart Lipton Disease Team Therapy Planning I hESC-derived NPCs Programmed with MEF2C for Cell Transplantation in Parkinson’s Disease $96,448
University of California, Los Angeles Bennett Novitch Basic Biology V In vitro modeling of human motor neuron disease $1,148,758
Stanford University Brian Rutt Tools and Technologies II Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters $1,833,348
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,737,694
Stanford University Calvin Kuo SEED Grant Differentiation of Human Embryonic Stem Cells to Intestinal Fates $554,176
University of Southern California Wange Lu Basic Biology I Defining the molecular mechanisms of somatic cell reprogramming $1,365,580
City of Hope Larry Couture Tools and Technologies III Development of a scalable, practical, and transferable GMP-compliant suspension culture-based differentiation process for cardiomyocyte production from human embryonic stem cells. $899,728
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
Gladstone Institutes Sheng Ding Basic Biology V A novel druggable mechanism to safeguard stem cell genome $1,423,800
Stanford University Michael Clarke Basic Biology III USP16 controls stem cell number: implications for Down Syndrome $1,263,826
University of California, Irvine Lisa Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $861,122
University of California, San Francisco Holger Willenbring SEED Grant Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia $329,245
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,075,251
University of California, Irvine Aileen Anderson Basic Biology II Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,256,194
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
University of Southern California David Woodley Disease Team Planning Clinical Regenerative Wound Healing With Stem Cells $33,626
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
University of California, San Francisco Tippi MacKenzie New Faculty Physician Scientist In Utero Embryonic Stem Cell Transplantation to Treat Congenital Anomalies $2,661,742
Escape Therapeutics, Inc Basil Hantash Transplantation Immunology Development of an immune tolerant hESC source for allogeneic cell therapy applications $1,453,040
Stanford University Aaron Hsueh SEED Grant Patient-specific cells with nuclear transfer $629,653
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,518,303
University of California, Irvine Leslie Thompson Early Translational II A hESc-based Development Candidate for Huntington's Disease $4,045,253
University of California, Davis Nancy Lane Disease Team Therapy Development - Research Treatment of osteoporosis with endogenous Mesenchymal stem cells $19,999,867
City of Hope Michael Barish Disease Team Planning Genetically-modified neural stem cells for treatment of high-grade glioma $55,000
Sanford-Burnham Medical Research Institute Mark Mercola Research Training II Type III CIRM Stem Cell Research Training Program $2,856,693
Stanford University Michele Calos Early Translational IV Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B $1,876,253
University of California, Santa Cruz Bin Chen New Faculty I Molecular mechanisms of neural stem cell differentiation in the developing brain $2,147,592
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $621,421
University of California, Davis Jan Nolta Early Translational I Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders $2,615,674
City of Hope Karen Aboody Disease Team Research I Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials $17,890,623
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
University of California, Los Angeles Carla Koehler Tools and Technologies III A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs $1,283,900
Gladstone Institutes Deepak Srivastava Shared Labs CIRM Shared Human Embryonic Stem Cell Core Laboratory $842,672
Humboldt State University Jacob Varkey Bridges CIRM Bridges to Stem Cell Research Certificate Program $3,335,098
Stanford University Irving Weissman Disease Team Therapy Development III Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors $11,650,152
Salk Institute for Biological Studies Lei Wang New Faculty I Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons $2,587,742
Scripps Research Institute Peter Schultz SEED Grant A Chemical Approach to Stem Cell Biology $748,944

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