All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Dennis Slamon Disease Team Research I THERAPEUTIC OPPORTUNITIES TO TARGET TUMOR INITIATING CELLS IN SOLID TUMORS $19,979,660
University of California, Los Angeles Sophie Deng Early Translational II Regeneration of Functional Human Corneal Epithelial Progenitor Cells $697,507
Gladstone Institutes Robert Mahley Research Training II CIRM Scholars Program $4,945,955
Stanford University Gary Steinberg Basic Biology V Paracrine and synaptic mechanisms underlying neural stem cell-mediated stroke recovery $1,178,370
University of California, Berkeley Irina Conboy New Faculty I Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues $2,246,020
University of California, Irvine Frank LaFerla Early Translational I Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
University of California, Davis A. Reddi SEED Grant hESCs for Articular Cartilage Regeneration $301,703
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
Gladstone Institutes Bruce Conklin New Cell Lines Induced Pluripotent Stem Cells for Cardiovascular Diagnostics $1,708,560
Scripps Research Institute Jeanne Loring Tools and Technologies III User-friendly predictive molecular diagnostic assays for quality control of stem cell derivatives for transplantation and drug discovery $1,784,052
California State University, San Marcos Bianca Mothe Bridges CIRM Bridges to the Stem Cell Research Training Grant $4,114,712
University of California, Irvine Michael Drake Major Facilities UC Irvine CIRM Institute $27,156,000
University of California, Los Angeles Gene Block Major Facilities UCLA CIRM Institute $19,854,900
Scripps Research Institute Kristin Baldwin New Faculty I Generating pluripotent cell lines from neurons. $2,786,560
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty Physician Scientist The generation and expansion of tissue-engineered small intestine from human stem/ progenitor cells: a preclinical study of functional translation $3,146,160
Salk Institute for Biological Studies Inder Verma Shared Labs Shared viral vector facility for genetic manipulation of human ES cell $1,844,315
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Buck Institute for Age Research Dale Bredesen SEED Grant Programmed Cell Death Pathways Activated in Embryonic Stem Cells $728,950
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
University of Southern California Martin Pera Basic Biology I The stem cell microenvironment in the maintenance of pluripotency and reprogramming $1,325,723
University of California, Irvine Henry Klassen Disease Team Planning Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $23,537
Cedars-Sinai Medical Center Clive Svendsen Tools and Technologies II Use of iPS cells (iPSCs) to develop novels tools for the treatment of spinal muscular atrophy. $1,933,022
University of California, San Diego Douglas Galasko Tissue Collection for Disease Modeling Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer's disease and cognitively healthy elderly controls $643,693
University of Southern California Andrew McMahon Shared Labs Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research $3,513,204
University of California, Irvine Kyoko Yokomori SEED Grant Derivation and characterization of human ES cells from FSHD embryos $607,200
University of California, Irvine Peter Bryant Training Grant I-1 Stem Cell Research Training Grant $1,935,487
University of California, San Diego Kun-Liang Guan Basic Biology II The function of YAP in human embryonic stem cells $1,245,693
Gladstone Institutes Sheng Ding Shared Labs Center for hESC Research $1,440,164
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of California, San Diego Alysson Muotri Early Translational IV A drug-screening platform for autism spectrum disorders using human astrocytes $1,656,456
University of California, Santa Cruz Joel Kubby Tools and Technologies I AO Wide-Field Microscope $549,551
University of California, San Francisco Andrew Leavitt Tools and Technologies III Small molecule tools and scale-up technologies to expand human umbilical cord blood stem and progenitor cells for clinical and research use $1,416,600
University of Southern California Qilong Ying New Faculty II Mechanisms Underlying the Diverse Functions of STAT3 in Embryonic Stem Cell Fate Regulation $2,261,174
University of California, San Diego Cornelis Murre SEED Grant Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells $473,952
University of California, San Diego Eric Adler Early Translational III Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
University of California, Los Angeles Sophie Deng Early Translational II Regeneration of Functional Human Corneal Epithelial Progenitor Cells $1,524,947
Scripps Research Institute Sheng Ding New Faculty I Reprogramming of human somatic cells back to pluripotent embryonic stem cells $1,393,876
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
University of California, Los Angeles Lili Yang Basic Biology V Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
University of California, San Francisco Tippi MacKenzie Transplantation Immunology Maternal and Fetal Immune Responses to In Utero Hematopoietic Stem Cell Transplantation $1,230,869
University of California, Los Angeles Donald Kohn Clinical Trial Stage Projects A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease $7,083,364
Stanford University Theo Palmer Comprehensive Grant Immunology of neural stem cell fate and function $2,396,000
University of California, Irvine Frank LaFerla SEED Grant Development of human ES cell lines as a model system for Alzheimer disease drug discovery $473,963
University of California, Davis John Laird Disease Team Therapy Development - Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $3,728,384
University of California, Los Angeles Donald Kohn Disease Team Research I Stem Cell Gene Therapy for Sickle Cell Disease $8,833,695
University of California, San Diego Catriona Jamieson SEED Grant Derivation and Characterization of Cancer Stem Cells from Human ES Cells $616,305
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,045
California Institute of Technology David Tirrell Basic Biology V Engineered matrices for control of lineage commitment in human pancreatic stem cells $526,896
Stanford University Karl Deisseroth New Faculty I Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny $2,424,209
University of California, San Diego Yang Xu Early Translational I Developing induced pluripotent stem cells into human therapeutics and disease models $5,165,028
University of California, Los Angeles Antoni Ribas New Faculty II Stem Cells for Immune System Regeneration to Fight Cancer $3,072,000
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
University of California, San Diego Steve Dowdy New Cell Lines Protein transduction of transcription factors: a non-genetic approach to generate new pluripotent cell lines from human skin. $1,073,585
University of California, Los Angeles James Dunn Tools and Technologies III Skin-derived precursor cells for the treatment of enteric neuromuscular dysfunction $1,818,751
City College Of San Francisco Carin Zimmerman Bridges Stem Cell Training Enhancement Program $2,704,836
Humboldt State University Jacob Varkey Bridges CIRM Bridges to Stem Cell Research Certificate Program $3,335,098
University of California, Merced John White Major Facilities Stem Cell Instrumentation Foundry $4,341,321
Sanford-Burnham Medical Research Institute Robert Wechsler-Reya Research Leadership The role of neural stem cells in cerebellar development, regeneration and tumorigenesis $5,226,050
Stanford University Alan Cheng New Faculty Physician Scientist Enhancing hair cell regeneration in mouse and human inner ear $3,091,595
Buck Institute for Age Research Xianmin Zeng Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $3,478,933
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
Human BioMolecular Research Institute John Cashman SEED Grant Discovering Potent Molecules with Human ESCs to Treat Heart Disease $688,274
Sanford-Burnham Medical Research Institute Stuart Lipton Disease Team Therapy Planning I hESC-derived NPCs Programmed with MEF2C for Cell Transplantation in Parkinson’s Disease $96,448
University of California, Los Angeles Michael Teitell Basic Biology I Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
Ludwig Institute for Cancer Research Webster Cavenee Disease Team Planning Stem Cell-Mediated Oncocidal Therapy of Primary & Metastatic Brain Tumors $3,867
Fluidigm Corporation Marc Unger Tools and Technologies II Development and Application of Versatile, Automated, Microfluidic Cell Culture System $1,939,236
Cellular Dynamics International Thomas Novak hiPSC Derivation Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to investigate multigenic diseases $16,000,000
Stanford University Helen Blau Tools and Technologies I Regulation of Stem Cell Fate in Bioengineered Arrays of Hydrogel Microwells $949,608
University of California, Los Angeles Siavash Kurdistani SEED Grant Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $549,698
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
University of California, Los Angeles Benhur Lee Basic Biology II The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $2,000,000
Stanford University Michael Clarke Basic Biology III USP16 controls stem cell number: implications for Down Syndrome $1,263,826
Gladstone Institutes Steven Finkbeiner Early Translational IV Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases $2,278,080
University of California, Davis Kit Lam Tools and Technologies I Discovery of adhesion ligands for pluripotent human stem cells $834,003
Stanford University Joseph Wu Tools and Technologies III Advanced animal model for predictive preclinical testing of engineered cardiac autografts and allografts $1,689,744
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,712,225
Sanford-Burnham Medical Research Institute Robert Oshima SEED Grant Trophoblast differentiation of human ES cells. $696,354
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
University of California, Irvine Henry Klassen Early Translational II Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $1,803,768
University of California, Riverside Douglas Ethell New Faculty I ES-Derived Cells for the Treatment of Alzheimer's Disease $621,639
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
University of California, Los Angeles Denis Evseenko Basic Biology V Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $411,330
University of California, San Diego Martin Marsala Transplantation Immunology Induction of immune tolerance after spinal grafting of human ES-derived neural precursors $1,387,800
California Institute for Biomedical Research Peter Schultz Late Stage Preclinical Projects Development of a Chondrogenic Drug Candidate Targeting Resident Mesenchymal Stem Cells for the Treatment of Osteoarthritis $1,667,832
University of California, San Francisco Samuel Pleasure Comprehensive Grant Human stem cell derived oligodendrocytes for treatment of stroke and MS $2,459,235
University of California, San Francisco Linda Giudice SEED Grant Human Embryonic Stem Cell Differentiation to Trophoblast: Basic Biology and Clinical Translation to Improve Human Fertility $614,784
University of California, Davis Nancy Lane Disease Team Therapy Development - Research Treatment of osteoporosis with endogenous Mesenchymal stem cells $19,999,867
Stanford University Irving Weissman Disease Team Research I Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells $18,759,276
University of California, Los Angeles Hanna Mikkola SEED Grant Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $550,241
Sanford-Burnham Medical Research Institute Mark Mercola Research Training II Type III CIRM Stem Cell Research Training Program $2,856,693
University of California, Irvine Lisa Flanagan Basic Biology V Molecular basis of plasma membrane characteristics reflecting stem cell fate potential $994,108
Gladstone Institutes Sheng Ding New Faculty I Reprogramming of human somatic cells back to pluripotent embryonic stem cells $1,320,101
Scripps Research Institute Jeanne Loring Early Translational I Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation $5,830,771
Gladstone Institutes Benoit Bruneau New Faculty II Induction of cardiogenesis in pluripotent cells via chromatin remodeling factors $2,723,653
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
University of California, San Francisco Susan Fisher New Cell Lines Optimization of Human Embryonic Stem Cell Derivation Techniques and Production/Distribution of GMP-Grade Lines $1,383,419
University of California, Davis J. Leach Tools and Technologies III Multi-modal technology for non-destructive characterization of bioengineered tissues $1,842,792
Pasadena City College Pamela Eversole-Cire Bridges Bridges to Stem Cell Research $3,823,076
University of California, Santa Barbara Glenn Lucas Major Facilities UC Santa Barbara Bio Sciences II $3,205,800

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