All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Scripps Research Institute Carlos Barbas Tools and Technologies I Development of a novel technology for precise, efficient, and safe genetic modification of stem cells $1,138,548
University of California, Davis John Laird Disease Team Therapy Development - Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $12,113,602
Sanford-Burnham Medical Research Institute Stuart Lipton Comprehensive Grant MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells $2,832,000
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,045
University of Southern California Toshio Miki Tools and Technologies III Development of a clinical-grade extracorporeal liver support system using human induced pluripotent stem cell-derived hepatic cells $1,257,372
University of California, San Diego Christian Metallo Basic Biology V Metabolic regulation of cardiac differentiation and maturation $1,124,834
University of California, Davis William Murphy Transplantation Immunology Donor natural killer (NK) cells as “veto” cells to promote donor-specific tolerance $1,257,601
Stanford University Renee Reijo Pera New Cell Lines Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype $1,409,243
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
University of California, Los Angeles Zack Jerome Comprehensive Grant Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
City College Of San Francisco Carin Zimmerman Bridges Stem Cell Training Enhancement Program $2,732,437
University of California, Santa Barbara Glenn Lucas Major Facilities UC Santa Barbara Bio Sciences II $3,205,800
Western University of Health Sciences Douglas Ethell New Faculty I ES-Derived Cells for the Treatment of Alzheimer's Disease $1,401,642
Stanford University John Cooke SEED Grant EC regeneration in cerebrovascular ischemia: role of NO $476,995
ViaCyte, Inc. Olivia Kelly Early Translational I Methods for detection and elimination of residual human embryonic stem cells in a differentiated cell product $5,405,397
University of California, San Diego Mana Parast New Faculty Physician Scientist Human pluripotent stem cell-based therapeutics for preeclampsia $2,974,750
University of California, Los Angeles Douglas Black Basic Biology II Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Planning {REDACTED} Heart Disease Regenerative Medicine Team Planning Award $38,980
University of California, Los Angeles Stanley Carmichael Tools and Technologies II Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
University of California, Santa Cruz Bin Chen SEED Grant In vitro differentiation of hESCs into corticospinal motor neurons $465,624
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $1,728,111
Beckman Research Institute of City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,849,452
The J. David Gladstone Institutes Warner Greene SEED Grant The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $717,363
University of California, Los Angeles Irvin Chen Early Translational from Disease Team Conversion HPSC based therapy for HIV disease using RNAi to CCR5. $1,505,000
University of California, Davis Alice Tarantal Tools and Technologies I In Vivo Imaging for the Detection and Quantitation of Transplanted Stem/Progenitor Cells in Nonhuman Primates $799,350
Stanford University Michele Calos Early Translational II Stem Cell Therapy for Duchenne Muscular Dystrophy $2,267,261
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
Children's Hospital of Los Angeles Markus Muschen Early Translational II Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication $850,769
University of California, Santa Cruz David Feldheim SEED Grant Assessing the role of Eph/ephrin signaling in hESC growth and differentiation $474,161
University of California, San Diego Cornelis Murre Basic Biology V Epigenetic mechanisms that enforce pluripotency in embryonic stem cells $1,161,000
University of California, San Diego Ying Liu Tools and Technologies I Generation of disease models for neurodegenerative disorders in hESCs by gene targeting $709,829
University of California, San Diego Lawrence Goldstein Disease Team Research I Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $5,694,308
Stanford University Irving Weissman Comprehensive Grant Prospective isolation of hESC-derived hematopoietic and cardiomyocyte stem cells $2,471,386
The J. David Gladstone Institutes Yadong Huang New Faculty II Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo $2,843,770
University of California, Los Angeles Samantha Butler Basic Biology V Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $545,962
Stanford University Robert Negrin Transplantation Immunology Regulatory T cell induced tolerance to ESC transplantation $1,383,147
The J. David Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $778,859
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
Stanford University Christopher Zarins Comprehensive Grant Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells $2,454,490
Humboldt State University Jacob Varkey Bridges CIRM Bridges to Stem Cell Research Certificate Program $3,335,098
University of California, Santa Cruz Margaret Delaney Major Facilities UC Santa Cruz IBSC Facility $7,191,950
University of California, Santa Cruz Camilla Forsberg New Faculty I Mechanisms of Stem Cell Fate Decisions $2,201,759
The J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $590,997
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
Scripps Health Darryl D'Lima Early Translational I Stem Cell-Based Therapy for Cartilage Regeneration and Osteoarthritis $3,118,431
University of California, San Francisco Ophir Klein New Faculty Physician Scientist Stem cell therapy for inflammatory bowel disease $3,084,000
University of California, Los Angeles Yong Kim Basic Biology II Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
Sanford-Burnham Medical Research Institute Stuart Lipton Disease Team Therapy Planning I hESC-derived NPCs Programmed with MEF2C for Cell Transplantation in Parkinson’s Disease $96,448
University of California, Irvine Leslie Thompson Disease Team Planning Huntington's Disease Team $41,953
University of California, San Diego Shu Chien Tools and Technologies II Development of Synthetic Microenvironments for Stem Cell Growth and Differentiation $1,706,628
University of California, San Francisco Thea Tlsty SEED Grant Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells. $614,784
University of Southern California Andrew McMahon Research Leadership 10 Repair and regeneration of the nephron $5,672,206
University of California, Los Angeles Owen Witte Shared Labs CIRM Shared Research Laboratories $1,751,297
Buck Institute for Age Research Xianmin Zeng Early Translational II Banking transplant ready dopaminergic neurons using a scalable process $4,983,013
The J. David Gladstone Institutes Robert Mahley Training Grant I-2 Gladstone CIRM Scholar Program $2,192,073
University of California, San Diego Deborah Spector Basic Biology III Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
Children's Hospital of Los Angeles Carolyn Lutzko Shared Labs hESC Facility $1,684,648
Stanford University Marius Wernig Tools and Technologies II Cellular tools to study brain diseases affecting synaptic transmission $1,664,382
Stanford University Phillip Yang SEED Grant In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $629,952
University of California, San Diego Lawrence Goldstein Early Translational from Disease Team Conversion Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $4,139,754
University of California, Berkeley David Schaffer Tools and Technologies I Directed Evolution of Novel AAV Variants for Enhanced Gene Targeting in Pluripotent Human Stem Cells and Investigation of Dopaminergic Neuron Differentiation $918,000
University of California, San Francisco John Murnane Basic Biology III Genomic instability during culturing of human embryonic stem cells $1,070,919
University of California, Los Angeles William Lowry SEED Grant Modeling Human Embryonic Development with Human Embryonic Stem Cells $528,096
University of California, San Francisco Mark Anderson Basic Biology V Generation of a functional thymus to induce immune tolerance to stem cell derivatives $1,191,000
Scripps Research Institute Jeanne Loring Tools and Technologies I The Stem Cell Matrix: a map of the molecular pathways that define pluripotent cells $1,133,552
University of California, Irvine Leslie Thompson New Cell Lines New Cell Lines for Huntington's Disease $1,302,526
University of California, Davis Vicki Wheelock Disease Team Therapy Development - Research MSC engineered to produce BDNF for the treatment of Huntington's disease $17,857,797
University of California, Irvine Peter Donovan Comprehensive Grant Improved hES Cell Growth and Differentiation $2,381,713
University of California, Davis Frederick Meyers Research Training II Stem Cell Training Program $5,822,412
Stanford University Anthony Oro Tools and Technologies III A Chromatin Context Tool for Predicting iPS Lineage Predisposition and Tissue Graftability $1,403,822
University of California, San Diego Benjamin Yu New Faculty II Regulation of Adult Stem Cell Proliferation by RAS and Cell-Permeable Proteins $3,017,978
University of California, San Diego Lawrence Goldstein Basic Biology V Elucidating pathways from hereditary Alzheimer mutations to pathological tau phenotypes $1,050,300
La Jolla Institute for Allergy and Immunology Anjana Rao Transplantation Immunology Generation of regulatory T cells by reprogramming $1,464,446
University of California, San Diego Sylvia Evans SEED Grant Specification of Ventricular Myocyte and Pacemaker Lineages Utilizing Human Embryonic Stem Cells $585,600
University of California, Irvine Hans Keirstead Comprehensive Grant hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,158,445
University of California, San Francisco A. Washington Major Facilities UCSF CIRM Building $34,862,400
University of California, Los Angeles Dana Jones New Faculty I Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $382,773
University of California, San Francisco Su Guo SEED Grant Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons $542,619
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
Scripps Research Institute Martin Friedlander Early Translational I Autologous Retinal Pigmented Epithelial Cells Derived from Induced Pluripotent Stem Cells for the Treatment of Atrophic Age Related Macular Degeneration $5,866,528
Stanford University Steven Artandi Basic Biology II Self-renewal and senescence in iPS cells derived from patients with a stem cell disease $931,285
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Planning I Stem Cells Secreting GDNF for the Treatment of ALS $63,487
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $12,131
University of California, Berkeley Steven Conolly Tools and Technologies II Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo $1,311,596
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $529,762
Numerate, Inc. John Griffin Early Translational IV Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin $630,269
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,721,129
University of California, Davis Mark Zern Early Translational II Liver Cell Transplantation $4,215,748
Sanford-Burnham Medical Research Institute Mark Mercola Training Grant I-2 Burnham Institute CIRM Stem Cell Training Grant (Type II) $1,061,865
University of California, San Diego Kun Zhang Basic Biology III Functional characterization of mutational load in nuclear reprogramming and differentiation $1,295,318
University of California, San Diego Karl Willert Tools and Technologies II Homologous recombination in human pluripotent stem cells using adeno-associated virus. $1,659,043
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $587,591
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $6,374,150
University of California, Los Angeles Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
The Salk Institute for Biological Studies Fred Gage Early Translational II Crosstalk: Inflammation in Parkinson’s disease (PD) in a humanized in vitro model $2,472,839
University of California, Berkeley Michael Rape Basic Biology III Ubiquitin-dependent control of hESC self-renewal and expansion $1,224,805

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