All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
ViaCyte, Inc. Howard Foyt Strategic Partnership I Preclinical and clinical testing of a stem cell-based combination product for insulin-dependent diabetes $10,075,070
University of California, San Francisco Arnold Kriegstein Comprehensive Grant Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells $2,410,874
University of Southern California Wange Lu SEED Grant Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling $624,000
University of California, San Francisco Mitchel Berger Disease Team Research I Stem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM) $6,214,914
University of California, Irvine Craig Walsh Early Translational III Multiple Sclerosis therapy: Human Pluripotent Stem Cell-Derived Neural Progenitor Cells $4,590,219
Children's Hospital of Los Angeles Carolyn Lutzko Shared Labs hESC Facility $1,684,648
University of California, San Diego Charles King Basic Biology III Biological relevance of microRNAs in hESC differentiation to endocrine pancreas $1,313,649
University of California, Los Angeles Siavash Kurdistani New Faculty I Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,063,450
University of California, San Diego Lawrence Goldstein Early Translational from Disease Team Conversion Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $3,995,136
J. David Gladstone Institutes Warner Greene Early Translational I Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation $1,324,011
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty II Mechanism of Tissue Engineered Small Intestine Formation $3,211,122
University of California, San Francisco Miguel Ramalho-Santos New Cell Lines Somatic cell age and memory in the generation of iPS cells $1,307,201
University of California, San Diego Mark Tuszynski Early Translational III Functional Neural Relay Formation by Human Neural Stem Cell Grafting in Spinal Cord Injury $4,600,447
Asterias Biotherapeutics Jane Lebkowski Strategic Partnership III Track A A Phase I/IIa Dose Escalation Safety Study of [REDACTED] in Patients with Cervical Sensorimotor Complete Spinal Cord Injury $14,323,318
University of California, Santa Cruz David Haussler Research Training II CIRM Training Program in Systems Biology of Stem cells $4,591,616
University of California, Berkeley Steven Conolly Tools and Technologies II Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo $1,311,596
University of California, San Francisco Mark Anderson Basic Biology V Generation of a functional thymus to induce immune tolerance to stem cell derivatives $1,191,000
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,721,129
University of California, Berkeley Ellen Robey SEED Grant In Vitro Differentiation of T cells from Human Embryonic Stem Cells. $477,894
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
Palo Alto Institute for Research and Education, Inc. Tony Wyss-Coray Basic Biology II Systemic Protein Factors as Modulators of the Aging Neurogenic Niche $1,159,806
California State University, Northridge Cindy Malone Bridges Bridges to Stem Cell Research $3,936,573
University of California, San Diego Karl Willert Tools and Technologies II Homologous recombination in human pluripotent stem cells using adeno-associated virus. $1,659,043
University of California, San Diego Lawrence Goldstein Basic Biology V Elucidating pathways from hereditary Alzheimer mutations to pathological tau phenotypes $1,050,300
University of California, Los Angeles Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
City of Hope Timothy O'Connor SEED Grant Sources of Genetic Instability in Human Embryonic Stem Cells. $327,311
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
University of California, San Francisco Arturo Alvarez-Buylla Early Translational II Inhibitory Nerve Cell Precursors: Dosing, Safety and Efficacy $1,564,016
University of California, Davis Mehrdad Abedi Disease Team Therapy Planning I RUNNING TITLE: Stem Cell Gene Therapy for HIV in AIDS Lymphoma Patients $66,880
University of California, San Francisco A. Washington Major Facilities UCSF CIRM Building $34,862,400
University of California, Irvine Orhan NALCIOGLU Tools and Technologies I A Multimodality Molecular Imaging Systen (MRSPECT) for in Vivo Stem Cell Tracking $719,798
University of California, San Francisco Jason Pomerantz New Faculty Physician Scientist Characterization of Human Skeletal Muscle Stem Cells for Clinical Application $3,084,000
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,460,822
Stanford University Joseph Wu SEED Grant In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $623,634
University of Southern California Roberta Brinton Creativity Awards CIRM STAR High School Summer Research and Creativity Program $322,253
University of California, Los Angeles Bruno Peault Early Translational II Harnessing native fat-residing stem cells for bone regeneration $5,359,076
University of Southern California Robert Maxson Training Grant I-1 CIRM Stem Cell Biology Training Grant $2,332,431
University of California, Irvine Leslie Thompson Disease Team Planning Huntington's Disease Team $41,953
University of California, Berkeley David Raulet Transplantation Immunology Inactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue $952,896
University of Southern California Andrew McMahon Research Leadership Repair and regeneration of the nephron $5,672,206
Stanford University Renee Reijo Pera Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,298,411
Children's Hospital of Los Angeles Elizabeth Lawlor SEED Grant hESC as tools to investigate the neural crest origin of Ewing's sarcoma $595,576
University of Southern California Mark Humayun Disease Team Research I Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $18,904,916
University of California, San Diego Eugene Yeo Early Translational III Molecules to Correct Aberrant RNA Signature in Human Diseased Neurons $1,532,323
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $1,976,931
Stanford University Sean Wu Basic Biology III Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells $1,264,248
University of California, Merced Jennifer Manilay New Faculty I Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance $1,576,404
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $6,374,150
Jackson Laboratory West Pali Kaur Early Translational I Mouse Models for Stem Cell Therapeutic Development $3,759,134
University of California, San Francisco Holger Willenbring New Faculty II Molecular dissection of adult liver regeneration to guide the generation of hepatocytes from pluripotent stem cells $2,832,008
Stanford University Renee Reijo Pera New Cell Lines Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype $1,409,243
Salk Institute for Biological Studies David Schubert Early Translational III Stem cell based small molecule therapy for Alzheimer's disease $1,673,757
City of Hope John Zaia Strategic Partnership III Track A A Phase I, Open-Label Study to Assess the Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells with Escalating Doses of Busulfan in HIV-1 (R5) Infected Subjects with Suboptim $5,583,438
Salk Institute for Biological Studies Juan Carlos Izpisua Belmonte Research Training II Training in the Biology of Human Embryonic Stem Cells and Emerging Technologies II $3,040,970
Stanford University Theo Palmer Tools and Technologies II Development of small molecule screens for autism using patient-derived iPS cells $1,797,606
Stanford University Helen Blau Basic Biology V Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging $1,175,357
Children's Hospital of Los Angeles David Warburton Shared Labs hESC Facility $1,750,259
Stanford University John Cooke SEED Grant EC regeneration in cerebrovascular ischemia: role of NO $476,995
J. David Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
University of California, Los Angeles Douglas Black Basic Biology II Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
California State University, Sacramento Jane Bruner Bridges Strengthening the Pipeline of Masters-level Scientific and Laboratory Personnel in Stem Cell Research $3,113,348
University of California, Santa Barbara Peter Coffey Research Leadership Development of Cellular Therapies for Retinal Disease $4,850,116
Palo Alto Institute for Research and Education, Inc. Thomas Rando Basic Biology V Molecular regulation of stem cell potency $966,510
Fluidigm Corporation Marc Unger Tools and Technologies I Scaleup of Versatile, Fully Automated, Microfluidic Cell Culture System $749,518
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $595,755
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
University of California, Irvine Brian Cummings Early Translational II Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767
StemCells, Inc. Alexandra Capela Disease Team Therapy Planning I Neuroprotection to treat Alzheimer's: a new paradigm using human central nervous system cells $90,101
University of Southern California Chrysostomos Nikias Major Facilities Broad CIRM Facility at USC $26,972,500
University of California, Los Angeles Michael Phelps Tools and Technologies I Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
University of California, San Francisco Ann Zovein New Faculty Physician Scientist Human endothelial reprogramming for hematopoietic stem cell therapy. $2,319,784
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $629,952
University of California, Davis Emanual Maverakis New Faculty Physician Scientist Tunable hydrogels for therapeutic delivery of multipotent stem cells. $2,772,000
Cedars-Sinai Medical Center Dan Gazit Early Translational II Systemic Adult Stem Cell Therapy for Osteoporosis-Related Vertebral Compression Fractures $1,927,698
University of California, Los Angeles Owen Witte Training Grant I-1 CIRM Type I Comprehensive Training Program $3,660,398
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $12,131
University of California, Los Angeles Gay Crooks Basic Biology III Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,252,857
University of California, Berkeley Ellen Robey Transplantation Immunology Human Immune System Mouse models as preclinical platforms for stem cell derived grafts $1,005,605
Numerate, Inc. John Griffin Early Translational IV Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin $520,015
Stanford University Judith Shizuru Transplantation Immunology Purified allogeneic hematopoietic stem cells as a platform for tolerance induction $1,233,275
Sanford-Burnham Medical Research Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $2,124,000
J. David Gladstone Institutes Deepak Srivastava Comprehensive Grant microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells $2,994,719
University of California, Santa Cruz David Feldheim SEED Grant Assessing the role of Eph/ephrin signaling in hESC growth and differentiation $474,161
University of California, San Diego Lawrence Goldstein Disease Team Research I Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $5,694,308
Stanford University Helen Blau Early Translational III Local Delivery of Rejuvenated Old Muscle Stem Cells to Increase Strength in Aged Patients $1,825,920
Scripps Research Institute Jeanne Loring Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $1,361,825
Scripps Research Institute Joel Gottesfeld Basic Biology III Triplet Repeat Instability in Human iPSCs $1,705,494
University of California, Los Angeles Hanna Mikkola New Faculty I Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells $4,179,598
Parkinson's Institute J. William Langston Early Translational I Using patient-specific iPSC derived dopaminergic neurons to overcome a major bottleneck in Parkinson's disease research and drug discovery $3,698,646
J. David Gladstone Institutes Yadong Huang New Faculty II Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo $2,843,770
J. David Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $778,859
Stanford University Judith Shizuru Disease Team Therapy Development - Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $19,068,382
Stanford University Theo Palmer Research Training II CIRM Training Program $7,475,333
University of California, Los Angeles Richard Gatti Tools and Technologies II Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
Salk Institute for Biological Studies Ronald Evans Basic Biology V Metabolically-driven epigenetic changes in iPSC reprogramming $1,491,900
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $1,679,818
J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $590,997
J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560

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