All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Sanford-Burnham Medical Research Institute Mark Mercola Research Training II Type III CIRM Stem Cell Research Training Program $2,856,693
University of California, Berkeley David Schaffer Tools and Technologies I Directed Evolution of Novel AAV Variants for Enhanced Gene Targeting in Pluripotent Human Stem Cells and Investigation of Dopaminergic Neuron Differentiation $918,000
University of California, Los Angeles Irvin Chen Disease Team Research I HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $1,976,931
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $2,760,540
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,039,058
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty II Mechanism of Tissue Engineered Small Intestine Formation $3,211,122
Pasadena City College Pamela Eversole-Cire Bridges Bridges to Stem Cell Research $3,823,076
University of California, Irvine Orhan NALCIOGLU Tools and Technologies I A Multimodality Molecular Imaging Systen (MRSPECT) for in Vivo Stem Cell Tracking $719,798
University of California, San Francisco Miguel Ramalho-Santos New Cell Lines Somatic cell age and memory in the generation of iPS cells $1,307,201
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,460,822
City of Hope John Zaia Strategic Partnership III Track A A Phase I, Open-Label Study to Assess the Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells with Escalating Doses of Busulfan in HIV-1 (R5) Infected Subjects with Suboptim $5,583,438
Stanford University Helen Blau Basic Biology V Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging $1,175,357
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Planning I Stem Cells Secreting GDNF for the Treatment of ALS $63,487
University of California, Berkeley David Raulet Transplantation Immunology Inactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue $952,896
University of California, Berkeley Ellen Robey SEED Grant In Vitro Differentiation of T cells from Human Embryonic Stem Cells. $477,894
University of California, San Francisco Arnold Kriegstein Comprehensive Grant Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells $2,410,874
Palo Alto Institute for Research and Education Tony Wyss-Coray Basic Biology II Systemic Protein Factors as Modulators of the Aging Neurogenic Niche $1,159,806
University of California, Los Angeles John Adams Alpha Stem Cell Clinics Alpha Stem Cell Clinic (ASCC) Consortium $8,000,000
Palo Alto Institute for Research and Education Thomas Rando Basic Biology V Molecular regulation of stem cell potency $966,510
University of Southern California Paula Cannon Tools and Technologies III Site-specific gene editing in hematopoietic stem cells as an anti-HIV therapy $1,499,400
Gladstone Institutes Robert Mahley Training Grant I-2 Gladstone CIRM Scholar Program $2,192,073
University of California, Los Angeles Siavash Kurdistani New Faculty I Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,063,450
City of Hope Timothy O'Connor SEED Grant Sources of Genetic Instability in Human Embryonic Stem Cells. $327,311
University of California, San Diego Deborah Spector Basic Biology III Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
Gladstone Institutes Warner Greene Early Translational I Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation $1,280,001
University of California, San Francisco Arturo Alvarez-Buylla Early Translational II Inhibitory Nerve Cell Precursors: Dosing, Safety and Efficacy $1,564,016
University of Southern California Chrysostomos Nikias Major Facilities Broad CIRM Facility at USC $26,972,500
The Scintillon Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $1,103,185
University of California, San Francisco Ann Zovein New Faculty Physician Scientist Human endothelial reprogramming for hematopoietic stem cell therapy. $2,319,784
University of California, San Francisco Arnold Kriegstein Early Translational III Human ES cell-derived MGE inhibitory interneuron transplantation for spinal cord injury $1,623,251
University of California, Berkeley Steven Conolly Tools and Technologies II Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo $1,311,596
Stanford University Joseph Wu SEED Grant In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $623,634
University of California, San Francisco John Murnane Basic Biology III Genomic instability during culturing of human embryonic stem cells $1,070,919
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,720,493
University of California, Los Angeles Bruno Peault Early Translational II Harnessing native fat-residing stem cells for bone regeneration $5,359,076
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $12,131
Numerate, Inc. John Griffin Early Translational IV Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin $520,015
University of California, Davis Vicki Wheelock Disease Team Therapy Development - Research MSC engineered to produce BDNF for the treatment of Huntington's disease $8,956,498
University of California, San Diego Karl Willert Tools and Technologies II Homologous recombination in human pluripotent stem cells using adeno-associated virus. $1,659,043
University of Southern California Wange Lu SEED Grant Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling $624,000
University of California, Davis Frederick Meyers Research Training II Stem Cell Training Program $5,822,412
University of California, Los Angeles Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
University of California, San Francisco Mitchel Berger Disease Team Research I Stem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM) $6,214,914
University of Southern California Mark Humayun Disease Team Research I Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $18,904,916
Scripps Research Institute Jeanne Loring Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $1,361,825
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells $4,179,598
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,260,360
University of California, San Francisco Holger Willenbring New Faculty II Molecular dissection of adult liver regeneration to guide the generation of hepatocytes from pluripotent stem cells $2,832,008
San Diego State University Ralph Feuer Bridges CIRM Stem Cell Internship Program $4,211,606
University of California, Los Angeles Michael Phelps Tools and Technologies I Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
Stanford University Theo Palmer New Cell Lines Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype $1,409,243
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
University of California, Berkeley Xavier Darzacq Research Leadership Single Molecule Biophysics and Biology of Cellular Identity $4,255,167
Salk Institute for Biological Studies Ronald Evans Basic Biology V Metabolically-driven epigenetic changes in iPSC reprogramming $1,491,900
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of Southern California Roberta Brinton Disease Team Therapy Planning I A CIRM Disease Team to Develop Allopregnanolone for Prevention and Treatment of Alzheimer's Disease $107,961
University of California, Berkeley Ellen Robey Transplantation Immunology Human Immune System Mouse models as preclinical platforms for stem cell derived grafts $1,005,605
Stanford University John Cooke SEED Grant EC regeneration in cerebrovascular ischemia: role of NO $476,995
Stanford University Theo Palmer Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,298,411
University of California, Los Angeles Douglas Black Basic Biology II Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
City of Hope John Zaia Alpha Stem Cell Clinics The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,000,000
University of California, Merced Kara McCloskey Basic Biology V Directed Differentiation of Specialized Endothelial Cells $476,052
University of Southern California Qilong Ying Tools and Technologies III Embryonic stem cell-based generation of small animal models for assessing human cellular therapies $1,334,160
Sanford-Burnham Medical Research Institute Mark Mercola Training Grant I-2 Burnham Institute CIRM Stem Cell Training Grant (Type II) $1,061,865
University of California, Merced Jennifer Manilay New Faculty I Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance $1,576,404
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $595,755
University of California, San Diego Kun Zhang Basic Biology III Functional characterization of mutational load in nuclear reprogramming and differentiation $1,295,318
Jackson Laboratory West Pali Kaur Early Translational I Mouse Models for Stem Cell Therapeutic Development $3,759,134
University of California, Irvine Brian Cummings Early Translational II Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767
University of California, San Francisco Jeffrey Bluestone Disease Team Planning A CIRM Disease Team for the Treatment and Cure of Diabetes $55,000
University of California, Davis Mehrdad Abedi Clinical Trial Stage Projects Stem Cell Gene Therapy for HIV Mediated by Lentivector Transduced, Pre-selected CD34+ Cells in AIDS lymphoma patients $8,414,265
Stanford University Michelle Monje New Faculty Physician Scientist White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain” $2,800,536
Stanford University Bertha Chen Early Translational III Autologous iPSC Therapy for Urinary Incontinence $5,025,428
Stanford University Theo Palmer Tools and Technologies II Development of small molecule screens for autism using patient-derived iPS cells $1,797,606
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $629,952
University of California, Berkeley Michael Rape Basic Biology III Ubiquitin-dependent control of hESC self-renewal and expansion $1,224,805
Children's Hospital of Los Angeles David Warburton Shared Labs hESC Facility $1,750,259
Cedars-Sinai Medical Center Dan Gazit Early Translational II Systemic Adult Stem Cell Therapy for Osteoporosis-Related Vertebral Compression Fractures $1,927,698
Sanford-Burnham Medical Research Institute Mark Mercola Disease Team Planning "Stem Cell Therapies for Heart Failure" $44,450
Sanford-Burnham Medical Research Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $1,020,815
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Development - Research Progenitor Cells Secreting GDNF for the Treatment of ALS $16,961,287
University of California, Santa Barbara Peter Coffey Research Leadership Development of Cellular Therapies for Retinal Disease $4,850,116
Children's Hospital of Los Angeles Elizabeth Lawlor SEED Grant hESC as tools to investigate the neural crest origin of Ewing's sarcoma $595,576
University of California, Berkeley Ellen Robey Research Training II Interdisciplinary Training in Stem Cell Biology, Engineering and Medicine $6,901,914
Fluidigm Corporation Marc Unger Tools and Technologies I Scaleup of Versatile, Fully Automated, Microfluidic Cell Culture System $749,518
Gamma Medica-Ideas, Inc. Douglas Wagenaar Tools and Technologies I A Novel SPECT Microscopy System for 3D Imaging of Single Stem Cells In Vivo $800,065
University of California, San Diego Lawrence Goldstein Disease Team Research I Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $5,694,308
University of California, Irvine Edwin Monuki New Faculty II Mechanisms in Choroid Plexus Epithelial Development $2,793,395
Gladstone Institutes Deepak Srivastava Shared Labs CIRM Shared Human Embryonic Stem Cell Core Laboratory $842,672
Stanford University Irving Weissman Disease Team Therapy Development III Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors $6,505,568
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,285,214
Gladstone Institutes Yadong Huang New Faculty II Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo $2,757,303
San Francisco State University Carmen Domingo Bridges Bridges to Stem Cell Research $4,201,420
Vala Sciences, Inc. Patrick McDonough Tools and Technologies I Optimization in the Identification, Selection and Induction of Maturation of Subtypes of Cardiomyocytes derived from Human Embryonic Stem Cells $870,717
Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $778,859
University of California, Los Angeles Gay Crooks Comprehensive Grant Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $1,653,416
Gladstone Institutes Todd McDevitt Research Leadership Engineering microscale tissue constructs from human pluripotent stem cells $6,368,285
University of California, Los Angeles Bennett Novitch Basic Biology V In vitro modeling of human motor neuron disease $1,148,758

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