Institution RFA PI Name Award Value City of Hope Alpha Stem Cell Clinics John Zaia The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,000,000 City of Hope Strategic Partnership III Track A John Zaia A Phase I, Open-Label Study to Assess the Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells with Escalating Doses of Busulfan in HIV-1 (R5) Infected Subjects with Suboptim $5,583,438 City of Hope Disease Team Research I Karen Aboody Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials $17,890,623 City of Hope Early Translational III Stephen Forman Targeting glioma cancer stem cells with receptor-engineered self-renewing memory T cells $5,217,004 City of Hope Tools and Technologies III Larry Couture Development of a scalable, practical, and transferable GMP-compliant suspension culture-based differentiation process for cardiomyocyte production from human embryonic stem cells. $899,728 City of Hope Early Translational II Yanhong Shi Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983 City of Hope Early Translational II David DiGiusto Development of RNA-based approaches to stem cell gene therapy for HIV $3,097,160 City of Hope Research Training II Michael Barish Research Training Program in Stem Cell Biology $2,500,143 City of Hope Disease Team Research I John Zaia ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,536,969 City of Hope Basic Biology IV Yanhong Shi Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,367,172 City of Hope SEED Grant Timothy O'Connor Sources of Genetic Instability in Human Embryonic Stem Cells. $327,311 City of Hope Creativity Awards Paul Salvaterra Creativity Award Program in Stem Cell Biology for California High School Students $271,857 City of Hope Tools and Technologies I Larry Couture Development of Suspension Adaptation, Scale-up cGMP Banking and Cell Characterization Technologies for hESC Lines $882,929 City of Hope Disease Team Planning Michael Barish Genetically-modified neural stem cells for treatment of high-grade glioma $55,000 City of Hope New Faculty I Tiziano Barberi Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy $131,840 Buck Institute for Age Research Early Translational II Xianmin Zeng Banking transplant ready dopaminergic neurons using a scalable process $4,983,013 City of Hope Basic Biology III Jiing-Kuan Yee Use of human iPS cells to study spinal muscular atrophy $1,268,868