Application Number Funding Recommendation Title Score RN1-00577 Recommended Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons 96 RN1-00561 Recommended Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells 94 RN1-00579 Recommended Trithorax and Polycomb methyltransferase complexes in cell fate determination. 92 RN1-00566 Recommended A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells 90 RN1-00584 Recommended Generating pluripotent cell lines from neurons. 90 RN1-00527 Recommended Molecular mechanisms involved in adult neural stem cell maintenance 90 RN1-00563 Not recommended Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults 88 RN1-00575 Recommended Genetic dissection of mesodermal commitment to the hematopoietic fates. 88 RN1-00548 Not recommended Laying the foundation for building a tooth: analysis of mammalian dental epithelial stem cells. 85 RN1-00529 Recommended Noncoding RNAs in Cell Fate Determination 85 RN1-00582 Not recommended The molecular basis underlying adult neurogenesis during regeneration and tissue renewal 83 RN1-00532 Recommended Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues 83 RN1-00564 Recommended In vitro reprogramming of mouse and human somatic cells to an embryonic state 82 RN1-00525 Recommended Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy 80 RN1-00544-A Recommended Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity 77 RN1-00544-B Recommended Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity 77 RN1-00533 Not recommended Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw 77 RN1-00530 Recommended Molecular mechanisms of neural stem cell differentiation in the developing brain 77 RN1-00567 Not recommended High throughput modeling of human neurodegenerative diseases in embryonic stem cells 75 RN1-00543 Not recommended Derivation and Characterization of Myeloproliferative Disorder Stem Cells From Human ES Cells 75 RN1-00557 Recommended Mechanisms of Hematopoietic stem cell Specification and Self-Renewal 73 RN1-00562 Recommended Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors 72 RN1-00562-1.2 Recommended Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors 72 RN1-00580 Not recommended Mechanisms underlying the diverse functions of STAT3 in pluripotent stem cell fate regulation 71 RN1-00572 Recommended Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells 69 RN1-00540 Recommended if funds allow Mechanisms of Stem Cell Fate Decisions 65 RN1-00536-A Recommended if funds allow Reprogramming of human somatic cells back to pluripotent embryonic stem cells 65 RN1-00536-B Recommended if funds allow Reprogramming of human somatic cells back to pluripotent embryonic stem cells 65 RN1-00581 Not recommended Regulation of Adult Stem Cell Proliferation and Number 63 RN1-00569 Not recommended Stem Cells for Immune System Regeneration to Fight Cancer 62 RN1-00535 Recommended if funds allow Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny 61 RN1-00553 Not recommended Mechanisms of NANOG Function in hESC 61 RN1-00550 Recommended Epigenetics in cancer stem cell initiation and clinical outcome prediction 61 RN1-00549 Not recommended Epigenetic determinants of normal and tumor stem cell biology 60 RN1-00554 Recommended if funds allow Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance 59 RN1-00526 Not recommended Reprogramming the Cancer Genome 0 RN1-00545 Not recommended Neural progenitors and Alzheimer's disease 0 RN1-00560 Not recommended Identification and functional analysis of stem cells in acute lymphoblastic leukemia 0 RN1-00539 Not recommended Directed Stem Cell Recruitment into the CNS in Response to Coxsackievirus Infection 0 RN1-00547 Not recommended Stem cell regeneration of neural circuits in murine Huntington's disease models 0 RN1-00574 Not recommended Analysis of MELK Function In Vivo in CNS Neural Progenitors And in Brain Tumors 0 RN1-00573 Not recommended Immune Regulation of Retinal Stem Cell Migration and Survival 0 RN1-00538-A Recommended if funds allow ES-Derived Cells for the Treatment of Alzheimer's Disease 47 RN1-00538-B Recommended if funds allow ES-Derived Cells for the Treatment of Alzheimer's Disease 47 RN1-00542 Not recommended Role of Apolipoprotein E in Hippocampal Neurogenesis and Its Therapeutic Potential in Alzheimer's Disease 0 RN1-00583 Not recommended Developing a transplantation therapy for Parkinson's disease using hESC-derived dopaminergic neurons. 0 RN1-00546 Not recommended The role of hyaluronan in regulation of differentiation of hESCs in hematopoietic lineage 0 RN1-00537 Not recommended Investigation of the Potential of Mouse Embryonic Stem Cells to Develop into Neuroendocrine Cells in Vitro 0 RN1-00578 Not recommended Tumor Neovascularization by a Non-angiogenic Mechanism: Plasticity-based Contributions by Brain Stem Cells. 0 RN1-00568 Not recommended Designing a microenvironment niche for hepatic differentiation of hESCs 0 RN1-00534 Not recommended Interactions Between Stem Cells and Cartilage in Health and Disease 0 RN1-00558 Not recommended Using Stem Cells to Make, Study, and Sort Useful Forebrain Cells 0 RN1-00531 Not recommended Inducing human embryonic stem cell differentiation into cardiomyocytes using extracellular matrix cues 0 RN1-00559 Not recommended Isolation of Fetal Hepatic Stem Cells for In Utero Transplantation 0 RN1-00570 Not recommended Investigation of the molecular pathways that integrate self-renewal and cell structure in embryonic stem cells. 0 RN1-00528 Not recommended Characterization of Immune Responses in Human Embryonic Stem Cells 0 RN1-00552 Not recommended Replenishing Dysfunctional Testes with Stem Cells 0 RN1-00555 Not recommended Building Cardiac Tissue from Stem Cells 0 RN1-00571 Not recommended A novel and generalizable organotypic slice model to evaluate stem cell potential for targeting pediatric brain tumors 0 RN1-00551 Not recommended Engraftment and Differentiation of Adult Human Stem Cells in Embryonic Eye 0 RN1-00565 Not recommended Stem Cell Differentiation in Cytopenias 0 RN1-00576 Not recommended A novel system for understanding the effects of natural genetic variation and epigenetics of stem cells. 0 RN1-00541 Not recommended Induction of tolerance in NOD mice using genetically engineered human adipose-derived mesenchymal stem cells 0