California Institute for regenerative medicine
The State stem cell agency
Childrens Hospital of Los Angeles
Awards as PI
Early Translational II
Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication
BCL6 enables Ph(+) acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition.
J Exp Med 2011
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia.
Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC.
Zebrafish screen identifies novel compound with selective toxicity against leukemia.
Control of B cell development by the histone H2A deubiquitinase MYSM1.