The J. David Gladstone Institutes

Award Value
Shared Labs: Deepak Srivastava CIRM Shared Human Embryonic Stem Cell Core Laboratory $1,698,515
Early Translational IV: Steven Finkbeiner Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases $2,278,080
Basic Biology III: Deepak Srivastava Mechanisms of Direct Cardiac Reprogramming $1,701,496
Research Leadership 14: Todd McDevitt Engineering microscale tissue constructs from human pluripotent stem cells $6,368,285
Research Training II: Robert Mahley CIRM Scholars Program $4,945,955
New Faculty II: Yadong Huang Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo $2,843,770
Basic Biology IV: Steven Finkbeiner Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
New Cell Lines: Bruce Conklin Induced Pluripotent Stem Cells for Cardiovascular Diagnostics $1,708,560
New Cell Lines: Robert Farese Establishment of Frontotemporal Dementia Patient-Specific Induced Pluripotent Stem (iPS) Cell Lines with Defined Genetic Mutations $1,696,424
New Cell Lines: Sheng Ding Derivation of New ICM-stage hESCs $778,859
Basic Biology V: Sheng Ding A novel druggable mechanism to safeguard stem cell genome $1,423,800
Basic Biology IV: Benoit Bruneau Epigenetic regulation of human cardiac differentiation $1,708,560
New Faculty I: Sheng Ding Reprogramming of human somatic cells back to pluripotent embryonic stem cells $1,414,664
SEED Grant: Warner Greene The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $717,363
Basic Biology IV: Sheng Ding A new paradigm of lineage-specific reprogramming $1,708,560
New Faculty II: Benoit Bruneau Induction of cardiogenesis in pluripotent cells via chromatin remodeling factors $2,815,309
Comprehensive Grant: Deepak Srivastava microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells $2,994,719
Early Translational III: Deepak Srivastava Direct Cardiac Reprogramming for Heart Regeneration $6,319,110
Early Translational I: Warner Greene Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation $1,324,011
Disease Team Planning: Deepak Srivastava Pluripotent Stem Cell–Based Therapy for Heart Disease $13,505
SEED Grant: Fen-Biao Gao MicroRNAs in Human Stem Cell Differentiation and Mental Disorders $748,800
Shared Labs: Sheng Ding Center for hESC Research $1,440,164
Shared Labs: Deepak Srivastava CIRM Shared Human Embryonic Stem Cell Core Laboratory $842,672
Training Grant I-2: Robert Mahley Gladstone CIRM Scholar Program $2,192,073
Research Leadership 12: Kevin Parker Engineering Cardiac Tissue for Regeneration and Drug Development $0
SEED Grant: Eric Verdin Role of HDAC in human stem cells pluripotentiality and differentiation $590,997
Creativity Awards: Shannon Noonan [REDACTED] Summer Scholars internship program $27,674
Total:
$51,808,345.00
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