CIRM Genomics Center of Excellence

Funding Type: 
Genomics Centers of Excellence Awards (R)
Grant Number: 
GC1R-06708
Investigator: 
ICOC Funds Committed: 
$0
Public Abstract: 
The proposed Genomics Center of Excellence will provide critical genomics and computational support to California stem cell investigators with the highest quality collaborative environment for cutting-edge, data-intensive genomics research. The Center builds upon the strong foundation of our existing BioSequencing Core resource located in the CIRM sponsored Major Facility. By leveraging our existing BioSequencing Core and other cores such as Bio-Engineering, Flow Cytometry, Proteomics, Metabolomics, Molecular Screening, Microscopy, FDA GMP compliant hESC & iPSC Derivation Labs and Banks, and our proven successful track record of collaborative stem cell research, we will provide an invaluable resource for California stem cell Investigators to advance the human stem cell field and stem cell biology genomics research, drive the development of genomics technology and techniques, and deepen our understanding of human disease, with a focus on translating basic research discoveries to the development of novel stem cell based therapeutics. The goals will be achieved through a coordinated approach that integrates: 1) extensive genomics based research collaborations, 2) next generation sequencing, 3) application of advanced bioinformatics analyses and interface with other leaders in the field such as ENCODE and the NIH Epigenome Project, 4) a proven genomics track-record and 5) our documented ability to identify and fund innovative stem cell research.
Statement of Benefit to California: 
The proposed Genomics Center of Excellence will provide critical genomics and computational support to California stem cell investigators with the highest quality collaborative environment for cutting-edge, data-intensive genomics research. The Center builds upon the strong foundation of our existing BioSequencing Core resource located in the CIRM sponsored Major Facility. By leveraging our existing BioSequencing Core and other cores such as Bio-Engineering, Flow Cytometry, Proteomics, Metabolomics, Molecular Screening, Microscopy, hESC & iPSC Derivation Labs and Banks, and our proven successful track record of collaborative stem cell research, we will provide an invaluable resource for California stem cell investigators to advance the human stem cell field and stem cell biology genomics research, drive the development of genomics technology and techniques, and deepen our understanding of human disease, with a focus on translating basic research discoveries to the development of novel stem cell based therapeutics. The goals will be achieved through a coordinated approach that integrates: 1) extensive genomics based research collaborations, 2) next generation sequencing, 3) application of advanced bioinformatics analyses and interface with other leaders in the field such as ENCODE and the NIH Epigenome Project, 4) a proven genomics track-record and 5) our documented ability to identify and fund innovative stem cell research.

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