2009 Annual Report: Spotlight on Macular Degeneration

Spotlight on Blindness: Macular Degeneration

On April 29, 2009 the CIRM governing board heard a Spotlight on Macular Degeneration featuring reseachers and a patient speaking about their hope for stem cell research. These are their stories.

Sharon Hayes
Pasadena, CA

The images on the playing cards wouldn’t come into focus, but Sharon Hayes kept trying to play bridge, making bidding mistakes as the game went along.

Finally, another bridge player had enough. “She said, ‘Sharon, you’ve got to go to the doctor right now.’ And we literally put down the cards and we went,” Hayes said.

That’s how the Pasadena-area woman learned she had wet macular degeneration in her left eye. But her eye had deteriorated beyond treatment. Leaky blood vessels growing beneath the retina left her with a gray cloud where people’s faces should be — at the very center of her vision.

Her other eye had the dry form of the disease. It advances more slowly, but is untreatable. When it converted to the wet form, her doctor injected it with a drug called Avastin, which stopped the vessel growth. Within five days, the sight in her right eye was 20/25 again, allowing her to continue painting and running her landscaping business.

She puts her hope in studies to find new and better treatments.

“The research is the most wonderful thing in the world. It’s going to be the answer to so many things,” she said. “If something new came out, I would try it in a heartbeat.”

CURING MACULAR DEGENERATION

Every day the cells essential for vision, called photoreceptors, shed their outer layer. And every day, a layer of cells just below these photoreceptor cells consumes the discarded shells. But in Macular Degeneration a sinister cycle emerges.

© 2013 California Institute for Regenerative Medicine