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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, Irvine Edwin Monuki New Faculty II Mechanisms in Choroid Plexus Epithelial Development $3,169,328
University of Southern California Gage DeKoeyer Crump New Faculty II Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw $2,396,871
University of California, San Francisco Jeremy Reiter New Faculty II High throughput modeling of human neurodegenerative diseases in embryonic stem cells $2,259,092
University of California, Merced Kara McCloskey New Faculty II Building Cardiac Tissue from Stem Cells and Natural Matrices $1,706,255
University of California, Davis Paul Knoepfler New Faculty II Molecular mechanisms governing hESC and iPS cell self-renewal and pluripotency $2,158,161
University of California, Berkeley Lin He New Faculty II The roles of non-coding RNAs in the self-renewal and differentiation of pluripotent stem cells $1,499,994
University of California, San Diego Mana Parast New Faculty II Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,253,580
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,250,251
University of California, San Francisco Emmanuelle Passegue New Faculty II Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults $2,274,368
University of Southern California Qilong Ying New Faculty II Mechanisms Underlying the Diverse Functions of STAT3 in Embryonic Stem Cell Fate Regulation $2,413,650
University of California, Los Angeles Antoni Ribas New Faculty II Stem Cells for Immune System Regeneration to Fight Cancer $3,247,000
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,725,830
The J. David Gladstone Institutes Benoit Bruneau New Faculty II Induction of cardiogenesis in pluripotent cells via chromatin remodeling factors $2,847,600
The J. David Gladstone Institutes Deepak Srivastava Comprehensive Grant microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells $3,164,000
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $561,082
Sanford-Burnham Medical Research Institute Stuart Lipton Comprehensive Grant MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells $3,035,996
University of California, San Francisco Susan Fisher New Cell Lines Optimization of Human Embryonic Stem Cell Derivation Techniques and Production/Distribution of GMP-Grade Lines $1,383,419
University of California, Los Angeles Guoping Fan Comprehensive Grant Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,516,613
Sanford-Burnham Medical Research Institute Alexey Terskikh SEED Grant Analysis of Candidate Neural Crest Cells Derived from Human ES Cells $759,000
Stanford University Irving Weissman Comprehensive Grant Prospective isolation of hESC-derived hematopoietic and cardiomyocyte stem cells $2,636,900
The J. David Gladstone Institutes Robert Farese New Cell Lines Establishment of Frontotemporal Dementia Patient-Specific Induced Pluripotent Stem (iPS) Cell Lines with Defined Genetic Mutations $1,708,560
University of California, San Francisco Susan Fisher Comprehensive Grant Constructing a fate map of the human embryo $2,532,388
University of California, Irvine Peter Donovan Comprehensive Grant Improved hES Cell Growth and Differentiation $2,509,438
The Salk Institute for Biological Studies Fred Gage New Cell Lines Development of Induced Pluripotent Stem Cells for Modeling Human Disease $1,737,720
The Salk Institute for Biological Studies Fred Gage Comprehensive Grant Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons $2,879,210
Stanford University Aaron Hsueh SEED Grant Patient-specific cells with nuclear transfer $656,074
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,566,702
University of California, San Francisco Long-cheng Li New Cell Lines Induction of pluripotent stem cells by small RNA-guided transcriptional activation $1,375,144
University of California, San Diego Lawrence Goldstein Comprehensive Grant Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer's Disease $2,512,664
University of Southern California Peter Laird SEED Grant Screening for Oncogenic Epigenetic Alterations in Human ES Cells $685,000
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $2,530,000
Stanford University Michael Longaker New Cell Lines Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts $1,424,412
University of California, San Diego Martin Marsala Comprehensive Grant Spinal ischemic paraplegia: modulation by human embryonic stem cell implant $2,445,716
University of California, Irvine Thomas Lane SEED Grant Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $425,594
University of California, Los Angeles Gay Crooks Comprehensive Grant Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $2,551,088
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $758,999
University of California, San Francisco Miguel Ramalho-Santos New Cell Lines Somatic cell age and memory in the generation of iPS cells $1,307,201
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $3,036,002
University of California, Davis Mark Zern Comprehensive Grant An in vitro and in vivo comparison among three different human hepatic stem cell populations $2,504,614
University of California, Riverside Frank Sauer SEED Grant Non-coding RNA as tool for the active control of stem cell differentiation $595,469
Stanford University Renee Reijo Pera New Cell Lines Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype $1,410,042
Stanford University Stefan Heller Comprehensive Grant Generation of inner ear sensory cells from human ES cells toward a cure for deafness $2,469,373
University of California, San Francisco Holger Willenbring SEED Grant Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia $342,962
The J. David Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $1,719,468
University of California, San Francisco Randall Lee Comprehensive Grant Embryonic Stem Cell-Derived Therapies Targeting Cardiac Ischemic Disease $2,524,617
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,387,508
Stanford University Roel Nusse Comprehensive Grant Guiding the developmental program of human embryonic stem cells by isolated Wnt factors $2,354,820
University of California, Davis Ebenezer Yamoah SEED Grant Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells $469,327
University of California, San Diego Binhai Zheng SEED Grant Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair $642,361
University of California, Davis Alice Tarantal Comprehensive Grant Preclinical Model for Labeling, Transplant, and In Vivo Imaging of Differentiated Human Embryonic Stem Cells $2,257,040
University of California, Irvine Kyoko Yokomori SEED Grant Derivation and characterization of human ES cells from FSHD embryos $632,500
University of California, Berkeley Carolyn Bertozzi SEED Grant Profiling surface glycans and glycoprotein expression of human embryonic stem cells $498,409
Stanford University Kenneth Weinberg SEED Grant Embryonic stem cell-derived thymic epithelial cells $658,057
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,570,000
Stanford University Joseph Wu SEED Grant In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity $658,123
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,628,635
The J. David Gladstone Institutes Fen-Biao Gao SEED Grant MicroRNAs in Human Stem Cell Differentiation and Mental Disorders $791,000
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $658,126
University of California, San Francisco Harold Bernstein Comprehensive Grant Modeling Myocardial Therapy with Human Embryonic Stem Cells $2,229,140
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $469,219
University of California, Irvine Leslie Thompson New Cell Lines New Cell Lines for Huntington's Disease $1,369,800
Stanford University Theo Palmer Comprehensive Grant Immunology of neural stem cell fate and function $2,501,125
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $251,088
University of California, Los Angeles Zack Jerome New Cell Lines Generation of clinical grade human iPS cells $1,382,400
Stanford University Phillip Yang SEED Grant In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction $658,125
University of California, San Francisco Samuel Pleasure Comprehensive Grant Human stem cell derived oligodendrocytes for treatment of stroke and MS $2,566,701
University of California, Irvine Vincent Procaccio SEED Grant Mitochondrial Dysfunction in Embryonic Stem Cells $632,500
Sanford-Burnham Medical Research Institute Zhuohua Zhang New Cell Lines Derivation of Parkinson's Disease Coded-Stem Cells (PD-SCs) $1,589,760
University of California, Los Angeles Zack Jerome Comprehensive Grant Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,516,831
University of California, Los Angeles Hanna Mikkola SEED Grant Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $577,037
University of California, Davis A. Reddi SEED Grant hESCs for Articular Cartilage Regeneration $367,650
Stanford University Julie Baker New Cell Lines Derivation of hESC Lines with Disease Lesions $1,424,412
University of California, Irvine Brian Cummings SEED Grant The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $619,223
Stanford University Christopher Zarins Comprehensive Grant Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells $2,618,704
Beckman Research Institute of City of Hope Timothy O'Connor SEED Grant Sources of Genetic Instability in Human Embryonic Stem Cells. $357,978
University of California, Irvine Grant MacGregor SEED Grant Production of Oocytes from Human ES Cells $623,781
Stanford University Michele Calos New Cell Lines Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses $1,406,875
University of California, Irvine Hans Keirstead Comprehensive Grant hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,396,932
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $618,901
University of California, Los Angeles Amander Clark New Cell Lines Generation of Pluripotent Cell Lines from Human Embryos $1,177,648
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $663,209
University of California, San Francisco Arnold Kriegstein Comprehensive Grant Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells $2,507,223
The J. David Gladstone Institutes Bruce Conklin New Cell Lines Induced Pluripotent Stem Cells for Cardiovascular Diagnostics $1,708,560
Stanford University Renee Reijo Pera Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,469,104
University of California, San Francisco Thea Tlsty SEED Grant Role of the tumor suppressor gene, p16INK4a, in regulating stem cell phenotypes in embryonic stem cells and human epithelial cells. $639,150
University of California, Irvine Charles Limoli SEED Grant Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $625,617
University of California, San Diego Steve Dowdy New Cell Lines Protein transduction of transcription factors: a non-genetic approach to generate new pluripotent cell lines from human skin. $1,387,800
University of California, Berkeley Ellen Robey SEED Grant In Vitro Differentiation of T cells from Human Embryonic Stem Cells. $499,999
The J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $790,999
University of California, San Diego Cornelis Murre SEED Grant Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells $538,211
Sanford-Burnham Medical Research Institute Robert Oshima SEED Grant Trophoblast differentiation of human ES cells. $748,240
The Salk Institute for Biological Studies Samuel Pfaff SEED Grant Gene regulatory mechanisms that control spinal neuron differentiation from hES cells. $807,749
University of California, San Francisco Didier Stainier SEED Grant Endodermal differentiation of human ES cells $635,242
University of California, Los Angeles Michael Teitell SEED Grant Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $635,024
Stanford University Julien Sage SEED Grant Functions of RB family proteins in human embryonic stem cells $520,777
Scripps Research Institute Peter Schultz SEED Grant A Chemical Approach to Stem Cell Biology $784,900
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $543,987
Ludwig Institute for Cancer Research Bing Ren SEED Grant Mapping the transcriptional regulatory elements in the genome of hESC $691,489
University of California, Irvine Frank LaFerla SEED Grant Development of human ES cell lines as a model system for Alzheimer disease drug discovery $492,750
University of California, San Francisco Linda Giudice SEED Grant Human Embryonic Stem Cell Differentiation to Trophoblast: Basic Biology and Clinical Translation to Improve Human Fertility $640,399
Total:
$154,359,612.00

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