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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, Los Angeles Gay Crooks Basic Biology III Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,375,983
University of California, Davis Alice Tarantal Early Translational I In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies $4,214,592
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $3,203,926
University of California, San Diego Eugene Yeo Basic Biology III Neural and general splicing factors control self-renewal, neural survival and differentiation $1,372,660
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
University of California, Merced Jennifer Manilay New Faculty I Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance $1,581,056
University of California, Santa Barbara Peter Coffey Research Leadership 2 Development of Cellular Therapies for Retinal Disease $4,880,116
Stanford University Joanna Wysocka New Faculty I Trithorax and Polycomb methyltransferase complexes in cell fate determination. $2,374,020
Scripps Research Institute Kristin Baldwin New Faculty I Generating pluripotent cell lines from neurons. $2,803,375
University of California, Los Angeles Dana Jones New Faculty I Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $2,675,234
University of California, Santa Cruz Bin Chen New Faculty I Molecular mechanisms of neural stem cell differentiation in the developing brain $2,200,715
University of California, Davis Jan Nolta Early Translational I Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders $2,753,559
Stanford University Karl Deisseroth New Faculty I Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny $3,154,719
University of California, Los Angeles Kathrin Plath New Faculty I In vitro reprogramming of mouse and human somatic cells to an embryonic state $2,229,427
University of Southern California Songtao Shi New Faculty I Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells $3,428,464
Beckman Research Institute of City of Hope Tiziano Barberi New Faculty I Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy $1,623,064
University of California, Davis Chong-Xian Pan New Faculty I Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells $2,567,397
The J. David Gladstone Institutes Warner Greene Early Translational I Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation $1,327,973
University of California, Los Angeles Michael Phelps Tools and Technologies I Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,096
The Jackson Laboratory West Leon Hall Early Translational I Mouse Models for Stem Cell Therapeutic Development $3,841,240
Vala Sciences, Inc. Patrick McDonough Tools and Technologies I Optimization in the Identification, Selection and Induction of Maturation of Subtypes of Cardiomyocytes derived from Human Embryonic Stem Cells $906,629
The Parkinson's Institute J. William Langston Early Translational I Using patient-specific iPSC derived dopaminergic neurons to overcome a major bottleneck in Parkinson's disease research and drug discovery $3,701,766
University of California, Berkeley Steven Conolly Tools and Technologies I Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scannerfor Tracking Stem Cells In Vivo $882,430
VistaGen Therapeutics, Inc. Kristina Bonham Tools and Technologies I Development of an hES Cell-Based Assay System for Hepatocyte Differentiation Studies and Predictive Toxicology Drug Screening $971,558
University of California, Davis Alice Tarantal Tools and Technologies I In Vivo Imaging for the Detection and Quantitation of Transplanted Stem/Progenitor Cells in Nonhuman Primates $842,149
University of California, Berkeley David Schaffer Tools and Technologies I Directed Evolution of Novel AAV Variants for Enhanced Gene Targeting in Pluripotent Human Stem Cells and Investigation of Dopaminergic Neuron Differentiation $918,000
University of Southern California Pin Wang Tools and Technologies I Development of Baculoviral Vectors for Gene Editing of Human Stem Cells $951,104
University of California, Los Angeles Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
University of California, Irvine Lisa Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $871,627
Stanford University Helen Blau Tools and Technologies I Regulation of Stem Cell Fate in Bioengineered Arrays of Hydrogel Microwells $949,608
University of California, Davis Kit Lam Tools and Technologies I Discovery of adhesion ligands for pluripotent human stem cells $835,540
Scripps Research Institute Carlos Barbas Tools and Technologies I Development of a novel technology for precise, efficient, and safe genetic modification of stem cells $1,146,312
Scripps Research Institute Jeanne Loring Tools and Technologies I The Stem Cell Matrix: a map of the molecular pathways that define pluripotent cells $1,141,124
Gamma Medica-Ideas, Inc. Douglas Wagenaar Tools and Technologies I A Novel SPECT Microscopy System for 3D Imaging of Single Stem Cells In Vivo $949,748
Beckman Research Institute of City of Hope Larry Couture Tools and Technologies I Development of Suspension Adaptation, Scale-up cGMP Banking and Cell Characterization Technologies for hESC Lines $882,929
University of California, San Diego Steve Dowdy Tools and Technologies I TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $925,200
University of California, Santa Barbara Dennis Clegg Tools and Technologies I Synthetic Matrices for Stem Cell Growth and Differentiation $599,998
University of California, San Diego Ying Liu Tools and Technologies I Generation of disease models for neurodegenerative disorders in hESCs by gene targeting $869,262
ViaCyte, Inc. Evert Kroon Tools and Technologies I Development of the Theracyte Cellular Encapsulation System for Delivery of human ES Cell-derived Pancreatic Islets and Progenitors. $827,072
Fluidigm Corporation Marc Unger Tools and Technologies I Scaleup of Versatile, Fully Automated, Microfluidic Cell Culture System $749,520
ViaCyte, Inc. Olivia Kelly Early Translational I Methods for detection and elimination of residual human embryonic stem cells in a differentiated cell product $5,405,397
University of California, Merced Michael Cleary Tools and Technologies I RNA Analysis by Biosynthetic Tagging (RABT): a tool for the identification of cell type-specific RNAs $483,803
Scripps Health Darryl D'Lima Early Translational I Stem Cell-Based Therapy for Cartilage Regeneration and Osteoarthritis $3,118,431
University of California, Santa Cruz Joel Kubby Tools and Technologies I AO Wide-Field Microscope $552,985
Scripps Research Institute Martin Friedlander Early Translational I Autologous Retinal Pigmented Epithelial Cells Derived from Induced Pluripotent Stem Cells for the Treatment of Atrophic Age Related Macular Degeneration $5,945,738
University of California, Irvine Orhan NALCIOGLU Tools and Technologies I A Multimodality Molecular Imaging Systen (MRSPECT) for in Vivo Stem Cell Tracking $719,798
The Salk Institute for Biological Studies Beverly Emerson SEED Grant Regulation of Specific Chromosomal Boundary Elements by CTCF Protein Complexes in Human Embryonic Stem Cells $678,788
Stanford University Thomas Wandless SEED Grant Reprogramming Differentiated Human Cells to a Pluripotent State $647,681
Stanford University Joachim Hallmayer Tissue Collection for Disease Modeling Induced pluripotent stem cells from children with autism spectrum disorders $530,265
University of California, Los Angeles Brigitte Gomperts Tissue Collection for Disease Modeling Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $934,515
Stanford University Joseph Wu Tissue Collection for Disease Modeling Tissue Collection for Accelerating iPSC Research in Cardiovascular Diseases $1,435,371
University of California, San Diego Kang Zhang Tissue Collection for Disease Modeling Generation of fibroblast cell lines in patients with common blinding eye diseases $1,034,452
University of California, San Diego Joseph Gleeson Tissue Collection for Disease Modeling CIRM Tissue Collection for Neurodevelopmental Disabilities $874,135
University of California, San Francisco Jacquelyn Maher Tissue Collection for Disease Modeling iPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis $865,370
University of California, San Diego Douglas Galasko Tissue Collection for Disease Modeling Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer's disease and cognitively healthy elderly controls $643,693
Cellular Dynamics International Thomas Novak hiPSC Derivation Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to investigate multigenic diseases $16,000,000
Coriell Institute for Medical Research Steven Madore hPSC Repository The CIRM Human Pluripotent Stem Cell Biorepository – A Resource for Safe Storage and Distribution of High Quality iPSCs $9,999,834
Total:
$123,949,250.00

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